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4 big warning signs that your thyroid is in trouble – and how to fix it. 👆🏼
#DaveAsprey #biohacking #biohacker #biohacked #thyroid #thyroidfunction #thyroidlevels #thyroidhormone #thyroidhealth
Connect with Dave Asprey!
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Telegram: https://t.me/aspreyofficial
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/
In this "Upgrade Spotlight" Episode of The Human Upgrade™...you'll find out how using a wearable nasal device can dramatically improve your breathing and sleep quality. CEO Michael Johnson joins the show from the Rhinomed headquarters near Melbourne, Australia. Rhinomed, the company behind Mute, pioneers the use of adjustable nasal devices for respiration, sleep, nasal diagnostics, and nasal drug delivery.
Mute sponsored this episode.
You’re going to learn how Mute's nasal device can help you get a much better night's sleep. Think of it as the first line of defense against snoring and sleep disruption. It’s a small device made of soft, adjustable polymers that sits comfortably inside your nose, increasing airflow and improving breathing.
SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS:
Go to https://mutesnoring.com and use code DAVE10 for 10% off and free shipping in the US, Canada, and Australia
Find more info & resources on the episode webpage: https://daveasprey.com/michael-johnson-mute-1028/
Dave Asprey’s NEW Book! “Smarter Not Harder: The Biohacker’s Guide to Getting the Body and Mind You Want” launches Feb. 28, 2023. https://www.amazon.com/dp/006320472X
Join us at the 9th Annual Biohacking Conference: https://biohackingconference.com
Connect with Dave Asprey!
Website: https://daveasprey.com
Telegram: https://t.me/aspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyof...
Twitter: https://twitter.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/thehumanupg... and https://m.facebook.com/Thehumanupgrade/
Nillion expands beyond blockchain to revolutionize decentralized computing.
(Dave Asprey partners with Nillion as an advisor and investor.)
IN THIS EPISODE OF THE HUMAN UPGRADE™...
… you’ll learn about the frontier of web3 and privacy and what happens to your private data (both on blockchains and in general). You’ll also find out how and why the future moves away from transactions (blockchain) and into computations (multi-party computation).
Think about where you store your identity and your deepest digital secrets. The current solutions aren’t great — in web2, the Big Tech ‘old guard’ has been quietly storing and monetizing your data for over a decade, and in web3, blockchains aren't designed to handle private data. A new algorithm, Nillion, inspired Conrad Whelan (the Founding Engineer of Uber) to come out of early retirement and do something about this.
This conversation looks at the data you unassumingly give away freely, and how it’s captured, held and used/computed on without your consent by large companies and other parties. Conrad believes in a future where your sensitive data and digital secrets can be fully controlled by you (and you alone) using web3 technology. This means you’d be the final gatekeeper of your data with the power to authenticate, authorize and use it as you see fit.
Conrad’s building that future as Nillion’s Founding Chief Technology Officer. His background includes electrical and computer engineering. He worked in the fields of computational electromagnetics before joining Uber as Founding Engineer. He’s developed, tested, deployed and architected software projects at all levels of the software stack as both an engineer and an engineering manager.
In 2016, he retired to focus his efforts on philanthropy and personal passion projects while keeping an eye on the tech world. The promise and potential global impact of Nillion enticed him out of retirement and into the company’s CTO role.
What Conrad is building at Nillion aims to:
-render both computational encryption and centralized storage of private data obsolete;
-fundamentally change the way private data is stored and processed;
-offer alternative non-blockchain ways of using decentralized nodes;
-serve as a ‘Meta Layer’ that provides new and additional functionality to existing blockchains; and
-enable a host of new real-world applications on its native public network (the Nillion Network).
Whatever your level of tech understanding, this discussion offers critical insights about the next big move in decentralized computing and data privacy.
Website: https://www.nillion.com
Twitter: https://twitter.com/nillionnetwork
Telegram: https://t.me/nillionnetwork
Discord: https://discord.com/invite/nillion#
YouTube: https://www.youtube.com/channe....l/UCKyQIOGz5dyIQXxQM
Find more info in the show notes on this episode's webpage: https://daveasprey.com/conrad-whelan-971/
Connect with Dave Asprey!
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Facebook: https://www.facebook.com/Daveaspreyof...
Twitter: https://twitter.com/daveasprey
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The Human Upgrade Podcast: https://www.instagram.com/thehumanupg... and https://m.facebook.com/Thehumanupgrade/
Save Up To $600: SUNLIGHTEN.COM/DAVE
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Most people see chronic fatigue and brain fog as permanent conditions caused by getting older, but this video cuts through that misconception by explaining that these symptoms are actually the direct result of damaged mitochondria piling up inside your cells because a specific longevity switch called mitophagy has been turned off.
Connect with Dave Asprey!
Website: https://daveasprey.com
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The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/discount/dave15?
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Join my Substack: https://substack.daveasprey.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/
Try TrueDark glasses: https://truedark.com
Try Danger Coffee: https://dangercoffee.com/discount/davetube
Try Suppgrade Labs: https://shopsuppgradelabs.com/
This video reveals that the brain has a documented neurological focus state driven by prefrontal cortex activation and norepinephrine signaling that most people access accidentally but can learn to trigger reliably. Dave explains the biological mechanism and the specific supplement and behavioral stack that activates this state within 20 minutes.
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/discount/dave15?
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Join my Substack: https://substack.daveasprey.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
Try TrueDark glasses: https://truedark.com
Try Suppgrade Labs: https://shopsuppgradelabs.com/
Try Aurowellness: https://aurowellness.com/
There is one molecule your body already makes that helps protect your cells from aging, but your production of it drops as you get older.
In this video, I explain why glutathione is known as the body’s master antioxidant and why it plays a critical role in cellular defense, mitochondrial energy, immune regulation, and liver detoxification.
You’ll discover why aging is not just your body “wearing out,” but the slow breakdown of your internal repair and antioxidant defense systems.
You’ll also learn:
Why oxidative stress damages mitochondria and accelerates aging
How glutathione helps protect cells from daily stress
Why your liver uses huge amounts of glutathione for detox support
The difference between oral, liposomal, IV, and topical glutathione
Why delivery matters if you want your body to actually use it
How to stack glutathione with sleep, protein, sunlight, training, and sauna
Connect with Dave Asprey!
Website: https://daveasprey.com
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Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/discount/dave15?
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Join my Substack: https://substack.daveasprey.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
In this episode of The Human Upgrade, Dr. Christy Sutton delves into the intricate relationship between iron, zinc, copper, and other essential minerals that play a crucial role in longevity and overall health. Drawing from her book, The Iron Curse, Dr. Sutton shares insights into how mineral imbalances can lead to conditions like iron overload, anemia, and other health issues, and how these imbalances affect the body’s ability to function optimally.
You'll learn about the significance of monitoring and managing your mineral levels, the impact of iron on cognitive function and aging, and the genetic factors that influence mineral absorption. Dr. Sutton also discusses the importance of personalized nutrition and supplementation in maintaining optimal health and preventing disease.
Dr. Sutton provides practical advice on how to recognize symptoms of mineral imbalances, the importance of regular lab testing, and the role of diet and lifestyle in managing these conditions. This episode is a must-listen for anyone interested in taking control of their health and longevity by understanding the foundational role of minerals in the body.
#ironsupply #irondeficiency #ironoverload #minerals #mineralimbalance
Sponsors:
Calroy | Head to https://calroy.com/dave for an exclusive discount.
Viome | Go to https://viome.com/dave to save $110 on the Full Body Intelligence Test.
Resources:
Buy Dr. Christy’s book: The Iron Curse
https://www.amazon.com/Iron-Cu....rse-Letting-Problems
Dr. Christy Sutton's Linktree: https://linktr.ee/drchristysutton
Follow Dr. Christy on Instagram: https://www.instagram.com/drchristysutton/
Dave's Linktree: https://linktr.ee/daveasprey
Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books
Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/
Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/
Supplements by Dave Asprey: https://shopsuppgradelabs.com/
Own an Upgrade Labs: https://ownanupgradelabs.com/
Chapters:
00:00:01 — Opening
00:02:44 — Introduction to Dr. Christy Sutton
00:05:50 — Iron Levels and Longevity
00:13:09 — Recognizing the Symptoms of High Iron
00:19:29 — Iron Levels in Children and the Risk of Misdiagnosis
00:32:35 — Managing High Iron through Diet and Supplementation
00:42:43 — Key Labs to Monitor for Iron and Mineral Levels
00:50:16 — The Role of Copper in Iron Absorption
01:06:42 — Closing Remarks
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
Twitter: https://twitter.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/
You are not eating because you are hungry. You are eating because you have been trained to, and the food industry designed it that way. This episode dismantles everything you thought you knew about hunger, weight loss, and metabolism, and gives you a science-backed framework to finally stop fighting your own biology.
Host Dave Asprey sits down with Dr. Jason Fung, a New York Times bestselling author, practicing nephrologist, and one of the most trusted voices in functional medicine and metabolic health. Dr. Fung completed medical school at the University of Toronto and a fellowship in nephrology at Stanford University. He is the author of multiple critically acclaimed books including The Obesity Code, The Diabetes Code, and his newest release The Hunger Code, and is the co-founder of The Fasting Method, a program designed to help people lose weight and reverse type 2 diabetes through fasting and real food nutrition. His work has helped millions break free from calorie restriction dogma for good.
Together, Dave and Dr. Fung expose the three types of hunger driving the obesity epidemic, why calorie restriction fails almost every time, and what ultra-processed foods actually do to your brain's reward system. They get into the real science of fasting, metabolism, hormonal signaling, GLP-1 drugs, food addiction, conditioned eating behavior, and how your physical environment is quietly sabotaging your results. If you are serious about biohacking your hunger, optimizing your body composition, and taking control of your biology without white-knuckling willpower, this episode delivers the tools you need.
You'll Learn:
-Why calorie restriction fails and what actually controls how much you eat
-The three types of hunger: homeostatic, hedonic, and conditioned, and how each one drives overeating
-How ultra-processed foods hijack your dopamine system and destroy satiety signals
-Why wiring your jaw shut or cutting your stomach still does not produce long-term weight loss
-What GLP-1 drugs like Ozempic actually reveal about hunger, metabolism, and the body fat thermostat
-How conditioned hunger works like Pavlov's dogs and practical strategies to reverse it
-The role of your physical environment in controlling food noise and cravings
-Why food addiction is real, and which foods are engineered to keep you hooked
-How fasting resets hunger signals, improves metabolic flexibility, and supports ketosis
-The mindset shift that makes healthy eating feel effortless instead of like deprivation
Resources:
• Check out all of Dr. Fung’s books and content at: https://www.doctorjasonfung.com/
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-cl....ean-nicotine-roadmap
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
Thank you to our sponsors!
- OneSkin | Get 15% off OneSkin with code DAVE at oneskin.co/DAVE.
- iRestore | Reverse hair loss with www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE
- Our Place | Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide
- fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.
Timestamps:
0:00 – Trailer
1:01 – Introduction
2:29 – The 3 Types of Hunger
4:41 – Conditioned Hunger
6:51 – Ultra-Processed Foods
11:47 – Dave's Personal Story
14:06 – The Calorie Debate
16:32 – Restricting Calories Doesn't Work
18:38 – The 3 Why's Framework
20:21 – Shame in Weight Loss
25:05 – GLP-1 Drugs
27:53 – Ranking the 3 Hungers
33:43 – Food Addiction
38:31 – Fake Fats & Fake Sweeteners
45:03 – 3 Golden Rules for Weight Loss
47:42 – Deprogramming Hunger
50:36 – Pavlok & Behavior Hacking
59:26 – Outro
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/DAVE15
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Join my Substack: https://substack.daveasprey.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
Try TrueDark glasses: https://truedark.com
Try Danger Coffee: https://dangercoffee.com/discount/davetube
Try Suppgrade Labs: https://shopsuppgradelabs.com/
Try Longevity Gummies: https://www.timeline.com/partners/dave-asprey
Most people see the physical decline of aging as an inevitable process that can only be managed with medications, but this video cuts through that assumption by explaining that the smartest minds in science, including multiple Nobel Prize winners, have identified a single root cause of aging tied to a specific molecule called NAD+.
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/discount/dave15?
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Join my Substack: https://substack.daveasprey.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
In this episode, Dr. Catharine Arnston joins Dave Asprey for an insightful conversation about the powerful health benefits of spirulina and chlorella. Catharine, founder and Chief Science Officer of ENERGYbits, shares her deep expertise on how these superfoods, packed with nutrients, can transform your health, support longevity, and boost mitochondrial function. They explore the unique properties of these algae supplements, including their ability to detoxify the body, improve energy production, and reduce inflammation. Whether you’re looking to enhance your fitness, adopt a more sustainable living approach, or discover the health benefits of chlorella and spirulina, this episode is packed with actionable insights.
Listeners will also dive into the spirulina benefits, from supporting brain health to improving cellular energy production. Catharine reveals how superoxide dismutase (SOD) in spirulina can help combat free radicals, promoting longer and healthier lives. They also discuss the environmental science behind algae farming and how incorporating these superfoods into your diet can be both sustainable and beneficial for your overall wellness.
If you’re curious about biohacking, longevity science, or how to use algae supplements for detoxification, this episode is a must-watch. From nutrition and dietary supplements to the science of green energy, chlorella, and spirulina, Catharine’s journey is a blueprint for anyone looking to improve their well-being through superfoods.
Resources:
ENERGYBits: Visit https://energybits.com/ and use code UPGRADE for 20% off your order.
ENERGYbits Instagram: https://www.instagram.com/energybits/
Dave Asprey’s Linktree: https://linktr.ee/daveasprey
Dave Asprey’s Book Smarter Not Harder: https://daveasprey.com/books
Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/
Join The Human Upgrade Podcast Live – Upgrade Collective: https://www.ourupgradecollective.com
Own an Upgrade Labs: https://ownanupgradelabs.com
Timestamps:
00:00 – You Won’t Believe This
00:39 – Introduction to Superfoods
01:24 – The Benefits of Algae
02:20 – Guest Introduction: Catharine Arnston
03:19 – Catharine’s Journey to Algae
04:16 – The Science Behind Algae
05:22 – Mitochondria and Algae
05:53 – The Role of Superoxide Dismutase (SOD)
06:24 – Alkaline Diets and Health
22:20 – Phycocyanin: The Cancer-Fighting Pigment
29:52 – Clinical Trials and Future Research
31:31 – Spirulina Efficacy Study
32:12 – Mitochondrial Health Insights
32:56 – Intermittent Fasting vs. Spirulina
35:27 – Testimonials and Real-Life Benefits
39:52 – Quality Control and Safety
43:31 – Skin Health and Algae
47:34 – Dosing and Usage Tips
48:18 – Brain Health and Recovery
50:57 – Aging and Biohacking
53:39 – Final Thoughts and Offers
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
Twitter: https://twitter.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
My favorite products: https://daveasprey.com/recommendation/
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/
Near-Infrared Light Therapy & EMF Shielding with SaunaSpace Founder Brian Richards
Your mitochondria are starving for a nutrient you've probably never tracked, and it's not a vitamin or a macro. This episode reveals how a forgotten 1910 therapy uses light to physically restructure water inside your cells, unlocking a mechanism for healing, detox, and mitochondria repair that most of biohacking has completely overlooked.
Go to https://sauna.space/ and use code ‘Dave’ for a 15% discount!
Host Dave Asprey sits down with Brian Richards, founder of SaunaSpace and a leading voice in incandescent light therapy and infrared sauna engineering. With a background in chemistry and organic synthesis, Brian spent over a decade building a science-backed alternative to LED-based light therapy rooted in full-spectrum incandescent light and deep radiant heat. After healing his own insomnia, adrenal fatigue, and brain fog through light and heat exposure, he developed the FireLight Spectrum, a technology engineered to restore what modern lighting strips away.
Dave and Brian trace incandescent light therapy back to Dr. John Harvey Kellogg's 1910 book on light therapeutics, and explain why the same institutional forces that suppressed chiropractic care and natural medicine buried this practice for over a century. They break down how near-infrared light penetrates the body to charge water into a more bioavailable state, boost glutathione and melatonin production, and repolarize cellular voltage for better metabolism and longevity. The conversation also covers why blue light from LEDs devastates hormones, testosterone, and fertility, how EMF exposure silently drains human performance, and why grounding and Faraday shielding matter more than most supplements on the market.
You'll Learn:
-Why near-infrared light functions as an essential nutrient your body cannot make without it
-How light physically restructures water to improve mitochondria function and cellular energy
-The suppressed history of Dr. Kellogg's incandescent light therapy and why it disappeared
-How blue light exposure crashes testosterone and disrupts fertility and hormone regulation
-Why EMF shielding and grounding are critical, overlooked tools for longevity and recovery
-How to use infrared light like a daily supplement instead of an occasional treatment
-Why carnivore-adjacent, nutrient-dense eating pairs naturally with light and heat therapy
Resources:
• Go to https://sauna.space/ and use code ‘Dave’ for a 15% discount!
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-cl....ean-nicotine-roadmap
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/davetube
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
• Dave Asprey’s BEYOND Conference: https://beyondconference.com
• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated
• Join My Substack (Live Access To Podcast Recordings): https://substack.daveasprey.com/
• Upgrade Labs: https://upgradelabs.com
Thank you to our sponsors!
- ELITE Performance Coaching | If you’d like to discover where you may be addicted to struggle, allergic to success, and what may be standing between you and your next breakthrough, visit FastestChange.com
- Longevity Farms | Go to getlongevityfarms.shop. Use code DAVE for 20% off your next order.
- Calroy | Go to calroy.com/dave for the clinical research, your discount, and a 45-day money-back guarantee.
- PredictiveMind™ | Get your Brain Pattern Mapping report at predictivemind.io/dave and use code DAVE for 10% off.
Timestamps:
00:00 – Trailer
00:46 – Meet Brian Richards
03:17 – Kellogg's Light Bath History
09:04 – Persecuted Light Pioneers
12:47 – Near-Infrared Science
16:07 – Blue Light Damage
19:26 – Sunscreen Myths
23:52 – Antidote & Melatonin
33:24 – Exclusion Zone Water
37:52 – Heart as a Vortex
41:47 – Fireplace & Infrared Deficiency
46:15 – FireLight Bulb Design
51:52 – EMF Shielding
55:16 – Faraday Cage & Grounding
1:05:51 – Sauna.Space Discount
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/discount/davetube
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Join my Substack: https://substack.daveasprey.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
Cardiologist Dr. Peter McCullough on mRNA Persistence, Nattokinase, and the Fight Over COVID-19 Treatment
Six years after standing before the US Senate and calling out the pandemic response in real time, Dr. Peter McCullough returns with new evidence on where the spike protein came from, how long it persists in the body after infection or vaccination, and what's being done to break it down. This episode traces the science from a 2015 gain-of-function paper to a patient still showing circulating spike protein 3.6 years after vaccination.
Get Dr. McCullough's free spike protein guide: myfreespikeguide.com
Host Dave Asprey sits down with Dr. Peter McCullough, a physician trained in internal medicine, cardiology, and epidemiology, and one of the most published and most censored voices of the COVID-19 pandemic. He authored the first multi-drug treatment protocol for COVID-19, testified before the US Senate in 2020 and again in 2025, and has published extensively in the peer-reviewed literature on vaccine safety, spike protein biology, and early treatment. His book Courage to Face COVID-19 and his most recent New York Times bestseller, Vaccines, Mythology, Ideology and Reality, examine the history and science behind vaccine policy.
Dave and Dr. McCullough trace the origins of the spike protein back to 2015 and 2016 research papers describing a lab-created, SARS-like coronavirus explicitly labeled "poised for human emergence," and discuss the funding, institutions, and researchers involved. They break down why synthetic mRNA vaccines resist the body's normal RNA breakdown process, what a patient case revealed about spike protein circulating 3.6 years after vaccination, and how nattokinase, a natural enzyme, has shown the ability to break the spike protein down. They also cover the suppression campaigns against ivermectin and hydroxychloroquine, the wartime propaganda origins of terms like "misinformation" and "anti-vaxxer," and what Dr. McCullough says he would do differently if he ran HHS. The conversation closes with new research on cognitive superagers, the small percentage of people who reach 100 with intact memory and health.
You'll Learn:
-Why 2015 and 2016 research papers described a lab-created coronavirus as "poised for human emergence" years before the pandemic
-Why synthetic mRNA in COVID-19 vaccines resists the body's natural RNA breakdown process
-What one patient's case revealed about spike protein still circulating 3.6 years after vaccination
-How nattokinase, a natural enzyme, has been shown to break down the spike protein
-Why the FDA and FTC targeted ivermectin, hydroxychloroquine, and companies selling nasal sprays during the pandemic
-The wartime propaganda origins of terms like "misinformation," "disinformation," and "anti-vaxxer"
-What Dr. McCullough says he would do first if he were running HHS
-What research on cognitive superagers reveals about the small number of people who reach 100 with intact health
Resources:
• Learn More About Dr. McCullough’s Work At: https://www.twc.health/pages/focal-points
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-cl....ean-nicotine-roadmap
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
Thank you to our sponsors!
- TrueDark | Visit truedark.com and use code DAVEASPREY15 (discount applies to all frames except Aegis)
- ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.
- Qualia | Go to qualialife.com/ASPREY for 50% off, and use code ASPREY for an additional 15% off.
- ENERGYbits | If you want a simpler, smarter way to support your body… this is it. Head to ENERGYbits.com and use code ASPREY for 20% off your order.
Timestamps:
00:00 – Trailer
00:43 – Intro
02:10 – 2020 Public Health Failures
05:07 – Vaccine History & Mythology
07:19 – Vaccine Hesitancy as Disease
13:12 – Masks & Lockdown Absurdity
18:03 – War on Hydroxychloroquine
23:56 – Ivermectin Suppression
28:58 – FTC Misinformation Crackdown
31:18 – Propaganda Terms Explained
39:55 – McCullough's Confidence & Career
43:08 – Spike Protein Origins
57:10 – Nattokinase & Spike Clearance
58:50 – mRNA Persistence in Body
1:11:50 – Fixing the System
1:17:32 – Political Divisiveness
1:22:41 – Secrets to Longevity
Website: https://daveasprey.com
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The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/
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40 Years of Zen: https://40yearsofzen.com
Discover the groundbreaking science behind fasting mimetics and how they can help you unlock the full benefits of intermittent fasting without extended food deprivation. In this episode of the Human Upgrade, Dave Asprey sits down with Chris Rhodes, a leading researcher in longevity supplements, to discuss his innovative work on Mimio, a cutting-edge formula designed to replicate the biological effects of a 36-hour fast—without actually fasting.
Learn how Mimio activates key longevity pathways like autophagy, boosts NAD production, and enhances metabolic health optimization to extend lifespan by an astonishing 96% in model organisms. Chris explains the science behind fasting-related compounds such as PEA and OEA, which help with appetite suppression, testosterone optimization, and improving cognitive function. The conversation dives deep into the role of biohacking for longevity, comparing the effects of Mimio to well-known longevity supplements like metformin and rapamycin.
If you’re looking to maximize the benefits of intermittent fasting, improve metabolic health, and tap into the latest breakthroughs in big data in longevity, this episode is packed with actionable insights.
Don’t miss this in-depth conversation on the future of fasting mimetics and metabolic health optimization.
*** Get 20% off Mimio at mimiohealth.sjv.io/3J9abX with code: DAVE ***
Resources:
• Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
• Mimio Instagram – https://www.instagram.com/mimiohealth/
• Mimio Website: https://mimiohealth.com/
• 2025 Biohacking Conference: https://biohackingconference.com/2025
• Danger Coffee: https://dangercoffee.com
• Dave Asprey’s Website: https://daveasprey.com
• Dave Asprey’s Linktree: https://linktr.ee/daveasprey
• Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com
• Own an Upgrade Labs: https://ownanupgradelabs.com
• Upgrade Labs: https://upgradelabs.com
• 40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com
Chapters:
00:00 – Intro
00:58 – Fasting & Longevity
01:88 – Optimal Fasting Length
03:39 – Alternate Day Fasting: Pros & Cons
05:50 – Key Fasting Compounds
07:34 – Spermidine & Longevity Molecules
11:41 – FDA Roadblocks on Natural Compounds
15:37 – AI, Big Data & Longevity Research
31:19 – Mimio’s Impact on Testosterone & Aging
35:16 – Longevity & Death Philosophy
36:48 – Biohacking Origins
37:03 – Metabolism & Cognitive Function
38:35 – Unexpected Effects of Fasting
40:43 – Fasting & Circadian Rhythms
43:09 – Mimio Science & Benefits
45:14 – Mimio in a Daily Routine
55:05 – Men vs. Women: Fasting Differences
01:02:23 – Future of Nutrition & Biohacking
01:07:21 – Conclusion & Discount Code
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
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YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/
In this episode of The Human Upgrade, Dr. Barry unveils the secrets of ancient energy practices that have been hidden for 5,000 years, revealing how they can transform your health, vitality, and overall life journey. He shares the “Great Eight,” a powerful framework for daily growth, and discusses how Energy Healing, Quantum Physics, and Ancient Wisdom intersect to unlock untapped potential.
From practical techniques for self-healing to cultivating serendipity and overcoming the limitations of the “animal brain,” this episode provides actionable strategies to help you achieve longevity, self-mastery, and peak performance. Dr. Barry’s blend of timeless teachings and modern insights offers a roadmap for profound personal growth and true balance in your life.
Whether you’re curious about unlocking new levels of energy or seeking tools for daily transformation, this episode delivers practical and empowering guidance for living your best life.
What You’ll Learn:
• How to apply the “Great Eight” framework for daily success and growth
• The science of Energy Healing and its role in longevity and vitality
• Insights into Quantum Physics and its connection to Ancient Wisdom
• Tools to cultivate serendipity, equanimity, and peak performance
• Practical steps to overcome limiting beliefs and unlock your full potential
SPONSORS:
Lumiram | Go to http://healthlighting.com/dave to save 10% on your order.
Calroy | Head to https://calroy.com/dave for an exclusive discount.
Resources:
2025 Biohacking Conference: https://biohackingconference.com/2025
Follow Dr. Barry on Instagram: https://www.instagram.com/energyforsuccess.official?igsh=eGcwZWhid3Q1M2Rm&utm_source=qr
Explore the Great 8 and Get Your Free Gift: https://energyforsuccess.com/dave/
Learn More About Energy Practices: https://energyforsuccess.com/
Danger Coffee: https://dangercoffee.com
Dave Asprey’s Website: https://daveasprey.com
Dave Asprey’s Book – Smarter Not Harder: https://daveasprey.com/books
Dave Asprey’s Linktree: https://linktr.ee/daveasprey
Upgrade Collective – Join The Human Upgrade Podcast Live: https://www.ourupgradecollective.com
Own an Upgrade Labs: https://ownanupgradelabs.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen – Neurofeedback Training for Advanced Cognitive Enhancement: https://40yearsofzen.com
Chapters:
00:00 Trailer
01:10 Introduction to Dr. Barry and His Journey
06:16 The Turning Point: Mrs. Rodriguez’s Story
09:04 Exploring Alternative Medicine Around the World
13:02 Discovering Ancient Chinese Healing Techniques
16:39 The Power of Quantum Physics and Lao Tzu’s Teachings
27:25 Personal Experiences with Energy Healing
36:35 The Great Eight: Structuring Your Day for Success
36:51 Introduction to Energy for Success
37:17 Understanding the Great Eight
38:23 The Matrix and Animal Brain
44:39 The Importance of Serendipity
49:35 Four Categories of People
53:02 Personal Experiences and Lessons
58:34 The Power of Energy Practices
01:07:06 Conclusion and Call to Action
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
Twitter: https://twitter.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/
Jonny Miller on Nervous System Mastery, Grief, and Why High Performers Can't Afford to Stay Stuck in Their Heads
Your nervous system is running every decision, relationship, and reaction in your life, and you won't notice how much it's costing you until something breaks. This episode gives you the exact framework for building real nervous system mastery instead of running on autopilot until it fails.
Host Dave Asprey sits down with Jonny Miller, host of the Inner Frontier Podcast and founder of Nervous System Mastery, who has taught more than 1,000 people how to build the skills of interoception, self-regulation, and emotional fluidity. A former Silicon Valley founder turned nervous system expert, Jonny brings a rare mix of rational, data-driven thinking and deep somatic work to a field most high performers avoid entirely.
They break down why interoception, self-regulation, and emotional fluidity are the three learnable skills behind every major shift in performance, relationships, and decision-making, and why most high achievers have spent their whole lives disconnected from what's happening below the neck. Jonny introduces the half-life of reactivity, his framework for measuring how quickly someone can move from triggered back to calm, and explains how free diving became his gateway into surrender, breath work, and pressure equalization as a form of high-stakes meditation. Dave shares his own parallel journey through nervous system work, including lessons from running 40 Years of Zen and a costly business betrayal that reshaped how he reads people. Dave and Jonny also open up about grief, including Jonny's experience losing his fiancée and later his mother, and how community and co-regulation shape how fast someone actually heals.
You'll Learn:
-Why interoception, self-regulation, and emotional fluidity are the three core skills behind nervous system mastery
-What the half-life of reactivity is and how to use it to measure real emotional progress
-How free diving works as a form of high-stakes meditation and a direct feedback loop for unclenching
-Why congruence between your inner and outer state matters more than staying composed under pressure
-How team intuition can be used as a practical filter in high-stakes hiring decisions
-Why co-regulation with friends and community can dramatically shorten the grieving process
-What Jonny's Breath Buddy device is designed to teach kids and families about nervous system regulation
Resources:
• Nervous System Mastery Course: https://www.nsmastery.com/
• Listen To Jonny’s Podcast ‘The Inner Frontier’ at: https://open.spotify.com/show/....1lGD5wIfhnE4bepja42C
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-cl....ean-nicotine-roadmap
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/davetube
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
Thank you to our sponsors!
- MOD | Visit mod.com for a consultation and get 10% off your first order plus free shipping with promo code DAVE.
- ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.
- BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle.
- Timeline | Visit timeline.com/dave to learn more about Mitopure and get 20% off your first order for a limited time.
Timestamps:
00:00 – Trailer
01:10 – Losing His Fiancée
04:28 – Nervous System Mastery
11:52 – Community & Co-Regulation
17:37 – From Head to Body
22:52 – Surrender & Free Diving
28:54 – Half-Life of Reactivity
35:33 – Congruence & the $100M Lesson
38:58 – Stupidity, Narcissism & Intuition
50:22 – Biohacking Trojan Horses
59:11 – Breath Buddy & Outro
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
STOP intermittent fasting if you think it automatically keeps you young. In this episode, you’ll learn why short-term fasting results can mislead long-term aging outcomes, and how duration, frequency, refeeding, and protein intake determine whether fasting supports longevity or quietly accelerates decline.
Host Dave Asprey sits down with Valter Longo, one of the world’s leading longevity researchers with over 30 years of experience studying aging, nutrition, and disease prevention. Dr. Longo is the Director of the Longevity Institute at the University of Southern California’s Leonard Davis School of Gerontology and the Director of the Longevity and Cancer Program at IFOM, the Italian Foundation for Cancer Research Institute of Molecular Oncology in Milan. He is the author of the bestselling book The Longevity Diet and was named one of TIME Magazine’s 50 most influential people in health care for his research on fasting-mimicking diets.
Together, Dave Asprey and Dr. Longo explain why many people focus too heavily on short-term effects and extrapolate them incorrectly across a lifetime. They break down how intermittent fasting differs biologically from multi-day fasting, why five-day fasting cycles trigger deeper cellular changes, and how insulin, IGF-1, mTOR, and growth hormone shape aging, regeneration, and disease risk over time.
The conversation covers protein and amino acid intake, muscle preservation, frailty risk, and the tradeoffs between strength, function, and longevity. They explore ketosis, fasting-mimicking diets, stem cell activation, mitochondrial function, neuroplasticity, and why equilibrium and cycling matter more than constant restriction. Dave and Valter also discuss supplements, nootropics, creatine, carnivore-style eating, metabolism, sleep optimization, and how AI may eventually personalize fasting and nutrition based on individual biology rather than population averages.
You’ll learn:
• Why short-term fasting benefits do not predict long-term longevity
• How fasting duration changes gene expression and cellular regeneration
• The difference between intermittent fasting and multi-day fasting
• How protein and amino acids influence mTOR, IGF-1, and aging
• Why muscle, strength, and longevity must be balanced, not maximized
• When ketosis overlaps with fasting and when it does not
• Why supplements can disrupt biological equilibrium
• How AI could support future personalization in fasting and nutrition
Resources:
• Learn More About Valter’s Work At: https://valterlongo.com/
• Join My Fasting Challenge: https://daveasprey.com/#14-day
• Get My 2026 Biohacking Trends Report: https://daveasprey.com/2026-bi....ohacking-trends-repo
• Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
Timestamps:
0:00 - Introduction & Aging Fundamentals
4:36 - Fasting Mimicking Diet Overview
7:03 - Insulin, IGF-1 & mTOR
11:03 - Body Fat & Fasting Frequency
17:08 - The Protein Debate
20:22 - Blue Zones & Centenarian Evidence
23:10 - Amino Acids & Leucine
30:30 - Growth Hormone & Longevity
34:01 - Five-Day Fasting Benefits
40:55 - Personalization & AI
42:29 - Plant-Based Concerns
49:07 - Fasting Risks & Limits
53:05 - Supplements & Equilibrium
1:03:05 - Ranking Longevity Pathways
1:05:05 - Modern Environmental Challenges
1:16:21 - Final Thoughts
Thank you to our sponsors!
• BEYOND Conference 2026 | Register now with code DAVE300 for $300 off at https://beyondconference.com/
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• Caldera + Lab | A small habit with big results. Go to https://CalderaLab.com/DAVE and use code DAVE for 20% off your first order.
• Timeline | Go to https://timeline.com/Dave for 20% off.
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
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The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/DAVE15
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Upgrade Collective: https://www.ourupgradecollective.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/DAVE15
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Upgrade Collective: https://www.ourupgradecollective.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
Jim Kwik on Memory, AI, and Why Natural Intelligence Beats Artificial Intelligence
Your brain is quietly outsourcing itself to AI, and you won't notice until it's gone. This episode gives you the exact framework to use artificial intelligence as a tool for brain optimization instead of a crutch that erodes your memory, focus, and critical thinking.
Host Dave Asprey sits down with Jim Kwik, one of the world's leading experts in memory improvement, brain optimization, and accelerated learning. For more than 30 years, Jim has served as the brain coach to professional athletes, political leaders, business magnates, and Hollywood icons, with corporate clients including Google, Nike, SpaceX, and Harvard. He hosts the Kwik Brain podcast with over 100 million downloads, reaches 200,000 people annually through live keynotes, and just wrapped his 14th annual Beyond Biohacking Conference with 5,000 attendees in Austin. Jim overcame a childhood brain injury that left him labeled "learning disabled," and turned that struggle into a mission he calls "no brain left behind."
They break down the MIT study showing that people who use AI to write and think score worse on memory and comprehension than those who rely on their own brains, and why that matters for anyone serious about longevity, human performance, and anti-aging. Jim introduces the concept of digital dementia and cognitive sovereignty, explaining how nootropics, neuroplasticity, and functional medicine can support your biology while AI still requires you to keep your own hardware sharp. They cover the MEDS Rx framework for brain optimization: meditation, exercise, diet, sleep optimization, and relationships, plus why mitochondria, metabolism, and inflammation from processed food directly impact your cognitive output. Jim also shares how his own kids use AI as a tutor rather than a replacement for thinking, and why sleep inertia and the first few minutes after waking set the tone for your entire day.
This is essential listening for anyone serious about biohacking, hacking their own brain, longevity, neuroplasticity, brain optimization, supplements, and building a Smarter Not Harder approach to human performance in the age of AI.
You'll Learn:
-Why the MIT study found AI users had weaker memory and comprehension than people who did the work themselves
-What digital dementia and digital deduction are, and how they quietly erode your cognitive muscles
-How to use AI as an augmented intelligence partner instead of a replacement for critical thinking
-The MEDS Rx framework for brain optimization: meditation, exercise, diet, sleep, and relationships
-Why the first few minutes after waking determine your focus and mood for the entire day
-How spaced repetition and AI-assisted learning can lock in new skills and behavior change faster
-The HUMAN framework for staying irreplaceable in a world run by algorithms
Resources:
• Learn More About Jim At: https://limitlessdaily.com/
• Follow Jim On Instagram At: https://www.instagram.com/jimkwik/
• Watch Jim On YouTube At: https://www.youtube.com/jimkwik
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-cl....ean-nicotine-roadmap
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/davetube
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
Thank you to our sponsors!
- KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off
- Neuronic | Go to www.neuronic.online Code DAVE for $100 off
- Our Place | Upgrade your kitchen with Our Place today. Visit fromourplace.com/DAVE and use code DAVE for 10% off sitewide.
- LMNT | Check it out at drinklmnt.com/DAVE. You'll get a free 8 count sample pack with any purchase.
Timestamps:
00:00 – Trailer
00:55 – Intro
06:54 – AI as Tool, Not Crutch
13:00 – Protecting Cognitive Sovereignty
21:28 – Digital Dementia Explained
27:13 – AI-Enhanced Learning Techniques
32:18 – Speed Listening and Reading
40:38 – Rapid Tips by Age
46:59 – Building an AI Second Brain
53:04 – Burnout and Brain Optimization
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Dave Asprey and Gabby Reece Talk Testosterone Therapy, Scream Cream, Autism as a Superpower, Cancer Protocols, and Surviving Fame in This Double Interview Episode
Mega-Episode time! Your hormones might be causing symptoms you've been blaming on aging, stress, or your heart. This double interview episode gives you a real look at biohacking from two different angles: cutting-edge longevity science and the lived experience of hormone optimization after 50.
Watch this episode on YouTube for the full video experience: https://www.youtube.com/@DaveAspreyBPR
Host Dave Asprey sits down with Gabby Reece, an American athletic icon, wellness entrepreneur, and one of the most influential voices in women's health, fitness, and performance. A former professional beach volleyball player who became Nike's first female spokesperson and shoe designer, Gabby set volleyball records at Florida State University that still stand today, and her signature Nike shoe line famously outsold Air Jordan during its release. She has since built a career at the intersection of performance and longevity, co-founding Hamilton House, Laird Superfood (NYSE: LSF), XPT, and HIGHX, and hosting both The Gabby Reece Show and the Proof of Practice podcast alongside leading voices in women's health and evidence-based performance. She is also a New York Times bestselling author. In this episode, Gabby turns the tables and interviews Dave herself, creating a rare two-way conversation between two people deeply immersed in human performance and biohacking.
You'll Learn:
-Why Gabby's heart arrhythmia turned out to be a hormone problem, not a cardiac one, and how testosterone fixed it when nothing else worked
-What "scream cream" actually is, how it works through vasodilation, and why doctors quietly prescribe it during hormone replacement therapy
-How mitochondria function as quantum systems and why improving their function can sharpen intuition, focus, and perception
-Why Dave believes autism comes paired with real cognitive advantages once the physical burden of the condition is addressed
-What Dave would actually do if diagnosed with cancer, from antifungal protocols to high-power infrared light and early detection screening
-The peptides Dave uses for mitochondrial renewal, including SS31 and lesser-known Russian bioregulators like epitalon and pinealon
-Why Dave avoids GLP-1 drugs despite believing low doses carry real longevity benefits
-How cyclical ketosis, fasting windows, and a carnivore-leaning diet support sustainable long-term metabolism
-Gabby's advice for raising confident daughters and why she believes success is less about deserving it and more about how you steward it
Resources:
• Learn More About Gabby’s Hamilton House At: https://hamiltonhouse.co/
• Watch Gabby’s Podcast At: https://www.youtube.com/@GabbyReece
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-cl....ean-nicotine-roadmap
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/davetube
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
Thank you to our sponsors!
- Beyond Wonderland Conference | Oct 13 - 14, 2026. Get your ticket now at wonderlandconference.com.
- Visit www.myvitalc.com/davesfav to unlock Dave’s discount
- Fatty15 | You can get an additional 15% off their 90-day subscription Starter Kit by going to fatty15.com DAVE and using code DAVE at checkout
- Omni-Biotic | Discover your formula at OmnibioticLife.com. Take 20% off your first order with code ASPREY.
15% off OneSkin with the code DAVE at https://www.oneskin.co/DAVE #oneskinpod
Timestamps:
00:00 – Trailer
00:52 – Gabby Interviews Dave
02:58 – Fatherhood and Teenagers
12:25 – Autism and Superpowers
17:02 – Quantum Biology & Biohacking
24:03 – Autism Epidemic and Hope
35:01 – Joe Rogan Feud
48:04 – Death, Immortality, Living to 180
56:24 – The Four F's Framework
1:04:55 – Cancer Prevention and Detection
1:18:20 – Travel Biohacking Tips
1:31:46 – Nothing You Can't Hack
1:41:23 – Peptides Deep Dive
1:52:33 – The Human Upgrade Podcast Starts
1:59:35 – Advice at Eighteen
2:10:03 – Fame and Holding Back
2:22:44 – Hormone Replacement Therapy
2:31:31 – Pursuit Over Happiness
2:43:02 – Advice for Tall Women
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Join my Substack: https://substack.daveasprey.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
Grab 20% off KORA Organics with code HUMAN20 at https://koraorganics.pxf.io/9VdD0E
Clean Living, Stress Reduction, Sleep, Skincare & Simple Wellness Habits with Miranda Kerr
Host Dave Asprey sits down with Miranda Kerr, founder of KORA Organics, entrepreneur, model, and longtime wellness advocate, to explore clean living, stress, sleep, skincare, meditation, parenting, and why her approach to health has become simpler over time.
Miranda shares how her mother’s cancer diagnosis when she was 16 changed the way her family looked at everyday ingredients and helped spark her lifelong interest in organic living, holistic health, and reducing unnecessary exposures. That experience later became a driving force behind KORA Organics and her focus on certified organic skincare.
Dave and Miranda discuss raising healthy kids without making health feel restrictive, navigating different health values within a family, and why acceptance matters when you cannot control another person’s choices.
The episode also covers clean beauty, plant-based retinol alternatives, non-nano zinc sunscreen, essential oils, rose quartz, intention, and the philosophy behind KORA Organics. Miranda also explains why constantly chasing new wellness tools eventually pushed her back toward a smaller set of foundational habits that consistently make her feel better.
This episode is essential listening for anyone interested in clean living, stress reduction, meditation, sleep, healthy parenting, skincare, organic beauty, biohacking, and building a wellness routine that supports your life rather than taking it over.
You’ll Learn:
-Why Miranda’s mother’s health scare changed the way she thought about food, skincare, and everyday ingredients
-Why her wellness routine has become simpler instead of more complicated over time
-The foundational habits Miranda prioritizes for energy, stress, sleep, and overall health
-How meditation, breathwork, morning sunlight, and evening light management fit into her daily routine
-How she teaches her children about healthy food without creating fear or restriction
-Why acceptance matters when your partner does not share the same health priorities
-How Miranda approaches clean beauty, organic skincare, retinol alternatives, and non-nano mineral sunscreen
-Why KORA Organics incorporates rose quartz, positive words, essential oils, and intention into its products
-How constantly experimenting with wellness tools can become counterproductive
-Why sunlight, sleep, food, relationships, and stress management remain the foundation even after years of exploring wellness
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Resources:
• Grab 20% Off KORA Organics with code HUMAN20 at https://koraorganics.pxf.io/9VdD0E
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-cl....ean-nicotine-roadmap
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/davetube
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
Thank you to our sponsors!
- KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off
- Neuronic | Go to www.neuronic.online Code DAVE for $100 off
- Puori | Use code DAVE at puori.com/DAVE to get 32% off your first Puori CP1 Pure Collagen order when you start a subscription. You save more than $26.
- LMNT | Right now, grab any LMNT drink mix and they'll throw in a free sample pack. Go to drinklmnt.com/dave to get yours.
Timestamps:
00:00 — Trailer
00:51 — Miranda’s Health Awakening
06:21 — Mind, Body & Crystals
13:12 — Roots of Positive Thinking
17:04 — The McDonald's Birthday Hack
22:36 — Acceptance in Relationships
28:34 — Intention Behind the Products
32:28 — Proving Organic Skincare Works
36:56 — Stress & Morning Rituals
42:09 — Back to Basics
48:17 — Health Without Public Pressure
51:06 — Closing Thoughts
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
Your gut already has its own version of Ozempic, and it’s been doing this job long before injections existed.
In this video, I explain how appetite is actually regulated, why synthetic shortcuts often create new problems over time, and what has quietly shut down the body’s natural satiety signals for so many people.
Once you understand the pathway drugs are trying to imitate, the question stops being “how do I eat less?” and becomes “why was my body blocked from doing this in the first place?”
This is about restoring a system, not overpowering it.
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/DAVE15
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Upgrade Collective: https://www.ourupgradecollective.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
The Hidden Causes of Brain Fog, Anxiety, and Chronic Illness: Mold, Parasites, Histamine, and Low Cortisol
Host Dave Asprey sits down with Dr. Jessica Peatross, a former hospitalist turned functional medicine powerhouse who walked away from a conventional medical career after discovering that 90% of disease traces back to lifestyle, environment, and the toxins most doctors ignore. After graduating magna cum laude and earning her medical degree from the University of Louisville, Dr. Jess pursued training in functional medicine, nutrigenomics, and alternative therapies, and now helps thousands of patients reverse chronic illness through her KillBindSweat method and WellnessPlus app. She is also the formulator and CMO of Aegis Formulas and a leading voice at international health conferences. If chronic illness, mold toxicity, or hormonal chaos is on your radar, she is the person you want in your corner.
Together, Dave and Dr. Jess go deep into the hidden drivers of mystery symptoms that functional medicine is finally starting to crack open. They cover why low cortisol is more dangerous than high cortisol, how histamine and mast cell activation syndrome explain everything from anxiety and brain fog to endometriosis and POTS, and why most "Lyme disease" is actually undiagnosed mold toxicity. They also break down the parasite epidemic hiding in plain sight across the United States, the B vitamin mistake making millions of people sicker, and why your metabolism, mitochondria, and mental health are all downstream of things your standard lab panel will never catch.
You'll Learn:
-Why everyone who is chronically sick has a low cortisol awakening response and what to do about it
-How histamine drives anxiety, racing thoughts, palpitations, bloating, skin issues, and hormonal chaos
-Why 90% of people diagnosed with Lyme disease actually have toxic mold and how to test for both
-The parasite epidemic in the U.S. and why standard testing misses most of it
-How the spike protein reactivates dormant viruses and feeds the histamine loop behind long COVID
-Why synthetic B6 causes the very neuropathy it is supposed to fix, and what to take instead
-The cortisol, adrenaline, and blood pressure connection that explains "wired but tired"
-How progesterone stabilizes mast cells and why estrogen dominance fuels inflammation and reactivity
-Why Dave Asprey uses low-dose cortisol, dexamethasone, and modafinil as part of his daily performance stack
-The mold binders that actually work, and which popular ones can harm hypermobile people
-How nicotine at low doses blocks spike protein from ACE2 receptors and protects the brain
-What the MTHFR gene, methylation, and folic acid have to do with breast cancer, depression, and estrogen detox
Resources:
• Go to https://drjessmd.com/ and use code ‘DRJESS’ at checkout
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-cl....ean-nicotine-roadmap
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
Thank you to our sponsors!
- iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE
- KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off
- Calroy | Go to Calroy.com/DAVE for exclusive discounts on Arterosil HP, Vascanox HP and all Calroy products.
- Cowboy Colostrum | Get your gut right by going to cowboycolostrum.com/asprey for 25% off of your entire order.
- Amp | If you're ready to make fitness fit into your life, go to amp.ai to check it out
Timestamps:
00:00 – Trailer
00:33 – Releasing Medical License
03:21 – Chronic Illness Root Causes
05:00 – Hospital Nutrition
08:11 – Dave's Health History
10:22 – Parasites
20:02 – Nicotine
23:19 – Low Blood Pressure & Minerals
28:09 – B Vitamins & Methylation
33:45 – Autism & Genetics
40:13 – Toxic Mold
43:11 – ADHD Misdiagnosis
48:27 – Histamine & Mast Cells
50:56 – Long COVID & Spike Protein
58:56 – Cortisol
1:03:56 – Lyme Disease
1:09:58 – Mold Testing & Binders
1:16:37 – Closing
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/discount/dave15?
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Join my Substack: https://substack.daveasprey.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
Microplastics are building up inside your brain, blood, and reproductive tissue, and most detox protocols do nothing to remove them. This episode gives you the cellular science behind why toxins accumulate, which three detox pathways control your ability to excrete them, and what the latest research shows actually moves microplastics, heavy metals, BPA, and benzene out of your body..
-For next week, 25% off all Mara Labs products when you go to www.mara-labs.com/DAVE and use code DAVE at checkout. After June 11th, the code will return to the standard 15% off.
Host Dave Asprey sits down with Dr. John Gildea, a Johns Hopkins-trained PhD with 60 scientific publications and over 20 NIH-funded studies, and David Roberts, co-founder of Mara Labs and co-creator of BrocElite, the only naturally derived stable form of sulforaphane available in a capsule. Together they bring decades of research-backed biohacking and functional medicine insight into one of the most pressing longevity conversations of our time.
They break down the lysosome, your cell's built-in incinerator, and explain exactly why it gets clogged with microplastics, advanced glycation end products, and other toxins that won't break down. New research shows that sulforaphane triggers a process called lysosomal surface translocation, which releases those trapped particles so your body can finally excrete them. An in-house Mara Labs study confirmed the excretion pathway: microplastics come out in feces. In the original study, the individual measured the highest microplastic levels ever recorded, and a repeat study a year later showed dramatically lower baseline microplastic levels, suggesting consistent use compounds the benefit over time.
You'll Learn:
-Why microplastics accumulate inside lysosomes and what sulforaphane does to release them
-How the three detox pathways, glutathione, glucuronidation, and sulfation, work together to remove every major class of toxin
-What an in-house study revealed about how and where microplastics actually leave the body
-How toxic estrogen metabolites form and why sulforaphane is the most effective natural tool to reroute them
-Why berberine supports sleep optimization, ketosis, and blocks a cancer growth pathway most drugs cannot touch
-How sulforaphane boosts BDNF and neuroplasticity at the cellular level
-What microplastic sources in your home, including your dryer, rugs, and receipts, are doing to your toxin load daily
-Why losing weight releases stored toxins and what to take to protect your brain and metabolism during fat loss
-How sulforaphane activates the same AMPK longevity pathways triggered by fasting without restricting food
Resources:
• For next week, 25% off all Mara Labs products when you go to www.mara-labs.com/DAVE and use code DAVE at checkout. After June 11th, the code will return to the standard 15% off.
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-cl....ean-nicotine-roadmap
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
Thank you to our sponsors!
- iRestore | Reverse hair loss at www.irestore.com/DAVE and get exclusive savings on the iRestore Elite, use code DAVE
- HeartMath | Go to https://www.heartmath.com/dave to save 15% off.
- Timeline | Go to timeline.com/dave and you’ll get an additional 20% off your first month
- Our Place | Stop cooking with toxic cookware and upgrade to Our Place today. With a 100-day risk-free trial, plus free shipping and returns, you can experience this game-changing cookware with zero risk. Visit: fromourplace.com/DAVE Use code: DAVE for 10% off sitewide
Timestamps:
00:00 – Trailer
01:55 – Intro & Context
04:48 – Microplastics & Sulforaphane
12:39 – Broccoli Sprouts Formulation
15:20 – Lab Origin Story
26:01 – Reducing Toxin Exposure
37:06 – Estrogen, Hormones & Berberine
52:46 – Autism, ADHD & Brain Health
59:01 – Wrap-Up
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/discount/dave15?
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Join my Substack: https://substack.daveasprey.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
In this episode of The Human Upgrade, we dive deep into the mystifying world of quantum energy with guest Philipp Samor von Holtzendorff-Fehling, founder of Leela Quantum Tech and Quantum Upgrade. Together with host Dave Asprey, Philipp unpacks the potential of harnessing quantum energy to enhance human performance, heal the body, and unlock higher consciousness.
Philipp discusses how quantum energy has always existed and how modern technology now allows us to access and concentrate it like never before. From personal anecdotes involving quantum blocks to the exploration of biofields and how they influence everything from athletic performance to wound healing, this episode is packed with eye-opening insights.
Dave shares his initial skepticism and eventual acceptance of quantum technology after experiencing the benefits firsthand. The conversation covers a range of fascinating topics including energy healing, distributed consciousness, quantum entanglement, and the ethics of working with energy fields. Plus, real-world examples like the flower experiment showcase the tangible effects of quantum energy in everyday life.
Sponsors:
Our Place | Head to https://fromourplace.com/ and use the code DAVE for 10% off your order.
Fatty15 | Go to https://fatty15.com/dave and save an extra $15 when you subscribe with code DAVE.
Resources:
Leela Quantum Tech: https://leelaq.com/
Quantum Upgrade: https://quantumupgrade.io/
Follow Philipp on Instagram: https://www.instagram.com/philipp_vhf/
Dave’s Linktree: https://linktr.ee/daveasprey
Dave Asprey’s Book ‘Smarter Not Harder’ is out now: https://daveasprey.com/books
Want to join The Human Upgrade Podcast Live? Join Our Upgrade Collective: https://www.ourupgradecollective.com/
Danger Coffee by Dave Asprey: https://www.instagram.com/dangercoffeeofficial/
Supplements by Dave Asprey: https://shopsuppgradelabs.com/
Own an Upgrade Labs: https://ownanupgradelabs.com/
Chapters:
00:00:00 — Ancient Alien Technology?
00:00:39 — Show Intro
00:01:33 — Dave’s Experience with Quantum Technology
00:04:45 — Introducing Philipp Samor von Holtzendorff-Fehling
00:05:38 — Quantum Technology Explained
00:06:35 — Personal Experiences with Quantum Devices
00:11:00 — Understanding Biofields and Energy Healing
00:15:21 — Philipp’s Journey to Quantum Technology
00:21:22 — Quantum Energy in Sports Performance
00:26:21 — Exploring Quantum Fields in Cells
00:27:11 — Quantum Blocks and Distributed Consciousness
00:27:53 — Quantum Energy and Flower Experiment
00:28:36 — Leela Quantum and Quantum Upgrade Explained
00:29:44 — Quantum Entanglement and Location
00:32:00 — Energy Fields and Geomagnetics
00:33:53 — Ethics and Integrity in Quantum Energy
00:36:19 — Scientific Evidence and Blood Studies
00:40:00 — Wound Healing and ATP Production
00:41:47 — Autism Clinical Trials and Brainwave Analysis
00:48:40 — Intuition and Frequency Selection
00:54:17 — Final Thoughts and Call to Action
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
Twitter: https://twitter.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ and https://m.facebook.com/Thehumanupgrade/
How to Reverse Cognitive Decline, Grow Your Hippocampus, and Protect Your Brain from Alzheimer's Disease with Nutrition, Exercise, Sleep, and Stress Reduction
Your brain is physically shrinking right now, and most people have no idea it's happening. In this episode, you will discover the exact mechanisms behind cognitive decline, why brain fog is always treatable, and the proven strategies to grow your brain back, protect your memory, and slash your Alzheimer's risk regardless of your genetics.
Host Dave Asprey sits down with Dr. Majid Fotuhi, a neuroscientist and neurologist who earned his PhD from Johns Hopkins University and his medical degree from Harvard Medical School. He currently serves as an adjunct professor at the Mind/Brain Institute at Johns Hopkins while also teaching at George Washington University and Harvard Medical School. With 37 years of experience in clinical practice, teaching, and neuroscience research, Dr. Fotuhi pioneered the Brain Fitness Program, a multidisciplinary approach to cognitive performance and brain vitality at any age that has produced measurable results documented in peer-reviewed journals. He is the author of three books including the bestselling The Invincible Brain and one of the world's leading experts on neuroplasticity, hippocampus growth, and successful aging. If anyone has earned the right to tell you your brain can get better, it is him.
Dr. Fotuhi and Dave break down why Alzheimer's is not a single disease but a soup of modifiable problems, why your lab results can show "normal" while your brain is starving, and how the five pillars of brain health connect directly to longevity, mitochondria function, and human performance. They also get into the brain effects of GLP-1s, the therapeutic promise of psychedelics like psilocybin and ketamine, the role of nootropics and supplements like B12, lithium orotate, and CoQ10, and why your VO2 max may be the single most important number for brain aging.
You'll Learn:
-Why 97% of Alzheimer's cases involve multiple modifiable causes and what to do about each one
-How to physically grow your hippocampus through exercise, meditation, and nutrition
-Why "normal" lab ranges are actively harming millions of people and what optimal actually looks like
-The 7 everyday things that are shrinking your brain right now
-How stress, loneliness, and isolation cause measurable brain atrophy
-Which supplements including B12, lithium orotate, CoQ10, and nootropics support long-term brain -health
-Why VO2 max predicts brain aging better than almost any other marker
-What psychedelics like psilocybin and ketamine actually do to your brain according to a Johns -Hopkins neurologist
-How the APOE4 gene affects Alzheimer's risk and why exercise can erase that risk entirely
-Why mitochondria health is the foundation of both brain function and longevity
Resources:
• Learn More About Dr. Fotuhi’s Work At: https://drfotuhi.com/
• Purchase Dr. Fotuhi’s New Book The Invincible Brain: https://a.co/d/0iHCgPpL
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-cl....ean-nicotine-roadmap
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
Thank you to our sponsors!
- Viome | Check it out at viome.com and use code 10DAVE for 10% off. It’s time to stop guessing and start knowing your body.
- BrainTap | Go to http://braintap.com/dave to get $100 off the BrainTap Power Bundle.
- Pique | Go to Piquelife.com/dave for 20% off.
- BodyHealth | Visit BodyHeath.com and use code DAVE20 for 20% off your first purchase
Timestamps:
00:00 – Trailer
00:59 – Intro
03:00 – Cannabis & Nicotine
04:15 – Understanding Alzheimer's
05:38 – Five Pillars Explained
07:55 – Best Cognitive Training
09:08 – Brain Size & Growth
12:36 – B12 & Lab Ranges
17:48 – Head-to-Toe Evaluation
24:17 – Sex & Brain Health
25:43 – Loneliness & Isolation
33:59 – ApoE4 Genetics
35:28 – Alzheimer's Declining
48:44 – Lithium & Brain
59:38 – VO2 Max & Fitness
1:06:42 – Psychedelics
1:09:38 – GLP-1s & Brain
1:12:38 – Closing & Action Steps
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/discount/dave15?
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Join my Substack: https://substack.daveasprey.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
Your mitochondria are the power plants of your cells, and when they break down, you lose energy, brain sharpness, and resilience against aging. In this episode, you’ll learn how to hack your mitochondria to supercharge human performance, prevent decline, and extend longevity with tools that are natural, effective, and backed by decades of research.
Listen to the FULL-LENGTH version of this episode on your favorite audio platform:
-Apple: https://podcasts.apple.com/us/....podcast/the-human-up
-Spotify: https://open.spotify.com/show/....2mkB9OoukPVKCTKSuAIg
Host Dave Asprey sits down with Catharine Arnston, founder of ENERGYbits, recent PhD graduate, and one of the world’s top experts on algae and functional medicine. Entering her 70th year without medications, with the cognition to finish a doctorate, and the health markers of someone decades younger, Catharine is living proof of how mitochondria and nutrition shape aging, brain optimization, and resilience.
Together they break down why mitochondria fail after age 30, how algae works as a master supplement to restore superoxide dismutase (SOD) and glutathione, and what happens when you give your cells the nutrients they’re wired to need. They uncover how mitochondria connect to energy, inflammation, metabolism, and cellular resilience. This is a masterclass in hacking energy and longevity, built for people who want to upgrade every system of the body and mind.
You’ll learn:
• Why mitochondria decline after age 30 and how to stop it
• The role of superoxide dismutase (SOD) and glutathione in preventing cellular “rust”
• How spirulina and chlorella outperform most supplements for detox and energy
• The connection between mitochondria and brain optimization
• Why men’s higher iron levels accelerate aging and how algae helps balance it
• How to build a mitochondria-first biohacking stack that actually works
This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality.
Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.
New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.
Keywords: Catharine Arnston, mitochondria, biohacking, algae supplements, spirulina, chlorella, superoxide dismutase, SOD, glutathione, metabolism, longevity, human performance, brain optimization, functional medicine, supplements, neuroplasticity, nootropics, ketosis, fasting, cold therapy, sleep optimization, carnivore, Danger Coffee, Smarter Not Harder, Dave Asprey, Human Upgrade podcast
**CTA: Go to https://energybits.com and use code ‘BEYOND’ for a 20% discount**
Timestamps:
00:00 — Trailer
01:22 — Intro
03:09 — Mitochondria Basics
05:28 — Free Radicals & Antioxidants
09:52 — Why Aging Accelerates
12:13 — Algae & Longevity
14:26 — Electron Transport Chain
18:15 — Stem Cells & Repair
21:15 — SOD, Glutathione & Manganese
29:22 — Spirulina vs. Chlorella
38:19 — Diet & Supplement Tips
41:06 — Final Takeaways
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/
Danger Coffee: https://dangercoffee.com/DAVE15
Dave Asprey’s BEYOND Conference: https://beyondconference.com/
Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/
Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15
Upgrade Collective: https://www.ourupgradecollective.com
Upgrade Labs: https://upgradelabs.com
40 Years of Zen: https://40yearsofzen.com
Back with another long one! Autism, mold poisoning, and cognitive decline share more root causes than most doctors admit, and this episode hands you the biohacking playbook to reverse all three.
Want to try Jenny's makeup and skincare line? Visit https://bit.ly/Formless-Beauty and use code DAVE to unlock a discount.
Host Dave Asprey sits down with Jenny McCarthy Wahlberg, a New York Times bestselling author, actress, comedian, and 14-season judge on The Masked Singer who became one of the most trusted voices in the autism community after her son's regression following a vaccine reaction. She documented his recovery in books including Louder Than Words and Healing and Preventing Autism, founded the vegan, cruelty-free beauty brand Formless Beauty, and now develops unscripted television, documentaries, and podcasts with her husband Donnie Wahlberg through their Work Baby Productions banner under a first look deal with Lionsgate.
Dave and Jenny trace her son's autism diagnosis back to a vaccine reaction and walk through the biohacking protocol that helped him recover, including candida detox, activated charcoal binders, collagen and hypermobility support, and hacking his gut with a low toxin diet that removed wheat and dairy. They connect autism to mitochondria energy collapse and neuroinflammation, and explain how nootropics like modafinil restore focus without the crash of stimulants.
The conversation moves into longevity and human performance strategies for adults, covering low dose Cialis for brain blood flow, DHEA and thyroid optimization for women over 35, peptide protocols including melanotan and Retatrutide, cyclical ketosis and fasting alternatives, and why hormone replacement therapy reverses aging instead of causing cancer.
You'll Learn:
-How mold and candida trigger PANS and PANDAS, and why they mimic autism symptoms
-Why activated charcoal timing determines whether it works as a binder
-The link between collagen, hypermobility, and leaky gut in autism and long-term brain function
-How modafinil, nicotine, and Cialis support brain optimization, focus, and mitochondria function
-Why hormone replacement therapy and DHEA reverse aging in women after 35
-The truth about ketosis supplements, structured water, and alkaline water myths
-How darkness, light exposure, and electrolytes rebuild sleep optimization and metabolism
Resources:
• Want To Try Jenny's Makeup And Skincare Sine? Visit https://bit.ly/Formless-Beauty and use code DAVE to unlock a discount.
• Check Out Formless Beauty On YouTube: https://www.youtube.com/@formlessbeauty
• Get My 2026 Clean Nicotine Roadmap | Enroll for free at https://daveasprey.com/2026-cl....ean-nicotine-roadmap
• Dave Asprey's Latest News | Go to https://daveasprey.com/ to join Inside Track today.
• Danger Coffee: https://dangercoffee.com/discount/davetube
• My Daily Supplements: SuppGrade Labs (15% Off)
• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)
Thank you to our sponsors!
- ZenBud | Dave’s Nervous System Biohack. Visit zenbud.health and use code DAVE15 at checkout for a discount.
- MOD | Visit https://mod.com/ for a consultation and get 10% off your first order plus free shipping with promo code DAVE.
- KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/and use code DAVE for 20% off
- Butcher Box | Go to ButcherBox.com/HUMANUPGRADE to get $20 off your first box, plus your choice of free ground beef for life, or free chicken thighs or top sirloins in every box for a year with free shipping always.
Timestamps:
00:00 – Trailer
01:20 – The Human Upgrade Starts
07:13 – Detoxing Candida: The Turnaround
15:00 – The Anti-Vaxxer Backlash
23:02 – The Many Flavors of Autism
29:36 – Powering Up the Autistic Brain
35:59 – The Bile & Binder Protocol
43:53 – Intuition, Trust & Integrity
53:40 – Building an Ethical Beauty Brand
58:34 – Sensory Sensitivities & Clean Living
01:04:00 – Modafinil: The Focus Drug
01:13:45 – Mold Illness, Memory & Brain Health
01:18:26 – Jenny McCarthy's Show Starts
01:22:45 – Dave's Mold Poisoning Story
01:31:04 – Nicotine, Ibogaine & Biohacking Extremes
01:38:33 – When Biohacking Goes Too Far
01:45:07 – Peptides, Hormones & Anti-Aging Hacks
01:52:24 – Hormone Replacement Therapy for Women
Connect with Dave Asprey!
Website: https://daveasprey.com
TikTok: https://www.tiktok.com/@daveaspreyofficial
Instagram: https://www.instagram.com/dave.asprey/
Facebook: https://www.facebook.com/Daveaspreyofficial/
X: https://x.com/daveasprey
YouTube: https://www.youtube.com/c/daveaspreybpr
I can’t believe who they picked
Thanks Top Troops for sponsoring this video. Download Top Troops at https://toptroops.onelink.me/JHnC/mrbeast or scan the QR code to get a FREE special Starter Pack for a limited time ad TopTroopsPartner
Thanks Samsung for the Tab S9s - the Galaxy AI features are cool too: https://smsng.us/MrBTabS9 SamsungGalaxyPartner
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MILK Chocolate 🍫 Win a Tesla or be in a MrBeast video - Buy now ▸ https://feastables.com
SUBSCRIBE TO GORDON!! @gordonramsay
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I can’t believe how intense this video got
The Samsung Galaxy Ring and Z Flip6 blew my mind in this video – you’ve gotta check them out. Head to Amazon to get yours and also see GalaxyAI in action: https://smsng.us/3LgiqJP ad samsungpartner
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Disclaimers: The heart rate software functions are not intended for use in the diagnosis of disease or other conditions, or in the cure, mitigation, treatment or prevention of disease. The Samsung Galaxy Ring requires a compatible smartphone and Samsung Health app.
How many YouTubers does it take to beat the world’s deadliest player?
Go get the new Feastables Caramel bar at Walmart, Target, or Albertsons :) 👉 https://fstbls.com/5mj6dv FeastablesPartner
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I can’t believe how far he got
Face your fears and start your business on Shopify right now 👉 https://shopify.com/mrbeast ad shopifypartner
Update: Nolan won the challenge, but you can still buy a MrBeast Football at https://go.shop.app/football
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These Minecraft builds blew my mind!
SUBSCRIBE OR YOU'LL HAVE BAD LUCK
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I can't believe how this ended
Go get yourself some Feastables peanut butter cups 👉 https://feastables.com/pages/find-a-store
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Thanks to The Battle Cats for sponsoring - Download and play The Battle Cats for free: https://pixly.go2cloud.org/SH3OO
The Battle Cats is celebrating their 8th Anniversary since the game’s release! Check out the game between now and October 10th to collect awesome gifts each day, take on limited anniversary stages, and get more free Cat Food rewards from the Wildcat Slots!
We’re playing Minecraft with some of the most insane texture and shader packs!
Shaders used in this video:
SEUS PTGI and SEUS Renewed - https://www.patreon.com/sonicether
BSL - https://www.patreon.com/capttatsu
Sildur's Vibrant Shaders - https://www.curseforge.com/min....ecraft/customization
Oceano Shaders - https://www.curseforge.com/min....ecraft/customization
Super Shaders - https://www.minecraftforum.net..../forums/mapping-and-
GLSL Acid Shaders - https://www.minecraftforum.net..../forums/mapping-and-
Texture Packs used in this video:
UMSOEA - https://www.patreon.com/umsoea
Brixel - https://www.patreon.com/wabbabrick
NAPP 512x - https://www.curseforge.com/min....ecraft/texture-packs
Dark Renaissance - https://www.curseforge.com/min....ecraft/texture-packs
BDcraft - https://bdcraft.net/
Luna 256x - https://www.patreon.com/lunahd
MS Painted - https://www.curseforge.com/min....ecraft/texture-packs
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I can't believe I gave away a private island. subscribe to help me pay for it
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Do you think you could have done all the levels?
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You get one shot. Hit the trick shot and win big or lose big. Are you making the shot?
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Complete your Valorant Battlestation — built for your Agent, ready for every fight. Both pieces are live now — snap on your gear and never miss a peek again. Get your VALORANT Limited Edition right now👇
Buy Anker Smart Display Hub: https://ankerfast.club/ANKERVA....LORANT_WestJett_6476
Buy Anker Laptop Smart Display Charger :https://ankerfast.club/ANKERVA....LORANT_WestJett_0289
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WestJett goes over PewDiePie being right about MrBeast
Jio H. Media: https://www.youtube.com/watch?v=qhImDq-jsuQ&t=42s
PewDiePie Was Right On What MrBeast Would Become...
#mrbeast #pewdiepie #drama
the 10 year build is actually mind blowing
FEASTABLES HAS THE BEST PEANUT BUTTER CUPS ON THE PLANET! Go find them at Walmart, Target, or 7Eleven 👉 https://fstbls.com/5mj6dv
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I cant believe we got that far
Write 4x faster with the Typeless voice keyboard. Just speak naturally and Typeless turns your speech into your best writing by understanding your intent: removing fillers, refining wording, and structuring your sentences. Works in any app on any device. Download Typeless here:
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If you noticed any trash in the video, we had a crew cleaning the beaches both before and after filming the video. All the garbage collected was then transported to a waste and recycling facility.
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The hotel at the end is worth the wait!
Download the Experian App: https://smart.link/n3op1gefxlzjn or Visit Experian.com/Boost.
“Results will vary. Not all payments are boost-eligible or considered by lenders. Credit Card offers are not available in all states. See website for details.”
Check out Conrad Maldives Rangali Island!
Facebook @conradmaldivesrangaliIsland
Youtube https://www.youtube.com/c/Conr....adMaldivesRangaliIsl
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No one could have predicted that outcome at the end lol
Feastables launched a new variety bag in Costco just in time for Halloween so you can give out mini sizes of our favorite flavors to trick-or-treaters! Find a store near you 👉 https://www.costco.com/w/-/locations FeastablesPartner
Incase you noticed the turbines moving during the Plane Pull section of the video, we just wanted to mention these engines were on idle therefore not sucking in any air. In order to control the planes braking system you have to have the engines on idle, which is standard in every strong man competition. We also had 2 pilots in the plane with full control of the aircraft along with personnel in contact and guiding them to ensure everything was safe for the kids, parents and crew we had on set that day.
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Buy Feastables!! https://feastables.com
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I started going insane at the end of this challenge
Bet you can't guess MrBeast's favorite flavor 👀- find out & get one for FREE at https://drinkcirkul.com/MrBeast or head to your local Walmart today to try Cirkul. ad cirkulpartner
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imagine if you could win $250,000 just by pressing a button lol
Buy MrBeast Lab Battle Fusion Swarms wherever you buy toys! https://www.moosetoys.com/prod....ucts/mrbeast-lab-swa
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Download Monster Legends now and get my monster! https://monsterlegends.onelink.me/X4Sc/March22
Monster Legends Social Media channels:
Instagram: http://bit.ly/MLInstagramIMCM
Discord: http://bit.ly/MLDiscordIMCM
Twitter: https://bit.ly/MLTwitterIMCM
We put the most EPIC never before seen Minecraft mobs in head to head battles! Watch to see the craziest battles and who wins TEN THOUSAND MrBeast Chocolate Bars!
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I'm not sure how they drove over that... it wasnt supposed to happen
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Congrats to all the winners from the last video!
~babystar22
~KevinAllen30
~MasonCunningham2020
~CheyniaWilson
~Dannyboiiii08
~Andresiux23
~AmandaLawrence6
~DonshaeHannah
~KirstenTeafatiller
~UndeadWiccan
~BenjaminPaz
~TylerSmith98
~JoseRangel11
~StorieDaise
~AlexiaClark1462
~MattyRivers
~onlymarkis
~ThomasWebster00
~NoahTribbleking
~JHix87252
~AntSmith1996
~AnthonyNino3
~JordanMetz
~xonviejade
~CMcCabe23
~Vonnny
~ROITDABBY
~PaulMeehan430
~MaximusButenko
~MaximusButenko
~ZacharyArmstead
~HunterLeitch
~ThornTheriot
~AliMakki
~Quann99
~Trawjr
~JohnNovits
~MCCARVES
~KazzVaz
~JenniJones400
~RaeZapien
~MrJazzy
~SageDelahousie
Buy my new chocolate bar: https://www.Feastables.com for a chance to win my chocolate factory in an upcoming video
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