I’m so happy all of these dogs will be going to great homes
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Get the Jinx dog food that was featured in this video! Jinx uses high quality proteins, superfoods and patented probiotics. Use code MRBEAST for 30% off at https://bit.ly/Jinx_MrBeast

Save $$$ on vet bills 🤑 click here to get Spot Pet Insurance! https://bit.ly/Spot_Pet_Insurance_MrBeast

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imagine being chained to a random stranger for 30 days lol

Next time you’re roasting s’mores, pick up Feastables! You can find our products at Albertsons, Walmart, or Target :) https://feastables.com/pages/find-a-store FeastablesPartner

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This was one of the hardest challenges we’ve ever done
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Go subscribe to Mark’s Channel! @MarkRober

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can the boys and i survive the arctic for 7 days

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50 YouTube legends all here in one video is actually insane 😅

Don't let pain stop your momentum. Keep the moment going with MOTRIN®- grab it on Amazon https://a.co/d/01LFWI3W

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I can’t believe they actually hired me lol
Try Immortals of Aveum today with a free trial for Playstation 5 and Xbox Series X|S, and a PC demo via Steam. https://bit.ly/3SV7oit SponsoredByEA ImmortalsofAveum ad

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I can’t believe how expensive the last house is

In case you want to buy the $139,000,000 House... https://www.instagram.com/1200belair/

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I finally made the Minecraft world I always wanted to make, 13 years later

Check out our new MrBeast Lab MEGA Mutators at Walmart! 👉 https://www.walmart.com/ip/MEG....A-PNTHR/19203372461?

The laptop I originally used to record the first episodes was destroyed, so we used the original seed and painstakingly recreated every block to make it the exact same that I had 13 years ago. If you want to play on this world, download it here: https://drive.google.com/file/....d/1ODgKBHIXMKU9v2IZi

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I am terrified of heights but I did this for you guys lol

Starforge Systems offers the best PCs in the universe at https://starforgepc.com/MrBeast starforgepartner

Normally 100 day challenges take 17 hours, but as it was extremely hot that day, we decided to shorten the length of the days and only give ourselves 13 hours to prepare for the dragon. Just wanted to be transparent if there was any confusion. Enjoy the video!

I want to give a huge shoutout to Cookie for being a part of this, check him out: @aCookieGod

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This video made me truly realize how awesome the future is going to be

Shopify technology made it possible for way more people to start businesses. Now it's your turn. Go to https://shopify.com/mrbeast to start your trial. ShopifyPartner

With Wing, Get food, groceries, and essentials in as little as 15 minutes. Find out if Wing currently delivers to your area. https://wing.com/mrbeast WingPartner

Big thank you to @Colossal for having us!

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I can’t believe somebody actually solved this…

Thanks to our friends at Salesforce, Slack and Lone Shark Games for making this insane challenge possible. Check out our detailed breakdown of the puzzle here: https://mrb.gg/p/puzzle

NO PURCHASE NECESSARY TO ENTER OR WIN. Takes place from 12:00 p.m. Eastern
Time (“ET”) on 9/2/26 to 11:59 a.m. ET on 9/2/27. Open to individuals 18+. See Official Rules
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Check out Colin:
https://www.youtube.com/@doctorxor
https://youtu.be/XCOkRKUe3Nc

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I was not prepared for how intense that ending was
Beast Games 2: Strong vs Smart is live now on Prime Video, go watch it right now for free: https://linktr.ee/beastgames

Special thanks to Radford Studios—the absolute best place to shoot any production. https://radfordsc.com/stages/

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Watching 100 people from every age compete was absolute chaos lol

This Sunday you could win $1,000,000 worth of prizes on Whatnot. I'm going live this Sunday at 10 AM PT. Download Whatnot, follow me on the app, and I will see you there :) https://www.whatnot.com/user/mrbeast

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Seeing these past contestants battle it out for $500,000 was wild
Launch a store on Shopify and I’ll buy from 100 random stores that do ▸ https://shopify.com/mrbeast ad shopifypartner

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what wins in a battle of survival, knowledge or resources?

Thanks to Bass Pro Shops for providing these teams with some awesome gear. Shop here: https://www.basspro.com/home

Disclaimer: We are contributing cash towards the wish of your choosing. Rules and conditions apply. Please visit https://bit.ly/MrB_Birthday_YT for additional rules and details.

The survivalists were told they’d be in a MrBeast Survival video so they packed for that. They were also given a small limited amount of food and gear like rice, beans, fishing gear, first aid kits, and a few tarps.

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imagine living in a grocery store

Special thanks to my friends at Square for supporting neighborhood businesses like The Bread Lady, Simply Natural Creamery, Blackbeard Coffee, and Blue Ox Games. Square is the all-in-one platform that helps businesses like these run smarter every day. Learn more → https://squareup.com

Coca-Cola is offering a chance to collect limited-edition Panini stickers for the FIFA World Cup 2026™. Peel a 20oz Coke label to start your collection and learn more at https://coca-cola.com/panini

Huge shoutout to Good Ranchers for supplying all the meat in this video. Turns out a lot of grocery store meat isn’t actually from the U.S., these guys are fixing that. Check them out at (https://go.goodranchers.com/beast], and save $40 off your first order by clicking the link or using code: BEAST at check out!

Special thanks to our friends at Unilever, Mondelez International, Campbell's, Henkel, Conagra Brands, Procter & Gamble, Kellogg's, and more for keeping us stocked—featuring brands like all Free Clear, Snuggle, Mama Mancini’s, Partanna, In The Raw, Takis, SpaghettiOs, Bigelow Tea, Dove, plus Hunt’s, Pringles, Tide, Bounty, Charmin, Febreze, Persil, AXE, Hellmann’s, Splenda, Entenmann’s, Bimbo Bakeries, Farmland Dairy, got2b, Wish-Bone, Hidden Valley, Ball Park, Quaker, Mezcla, Freestyle, Lull, and Coleman.

We actually put up TV commercials, radio ads, and flyers all around town the week before to get a bunch of random shoppers in the door and offer them the chance to compete in this video! The shoppers who chose to stay and compete all went through the usual review process for any of our videos and had access to the same resources (medics, mental health counselor, etc) as contestants in other videos.

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This video is an educational documentary designed to inform and entertain, and is compliant with all YouTube community and advertiser-friendly guidelines

MrBeast is the biggest YouTuber on the planet. But over the past few years, his once squeaky-clean reputation has taken a serious hit.

In this video, we take a closer look at the claims, controversies, and other incidents connected to MrBeast using publicly available information, reports, and online material.

Nothing in this video should be interpreted as stating unproven allegations as fact. Any claims concerning criminal or unlawful conduct are presented as allegations unless they have been established by a court or otherwise confirmed by reliable public records. This video is intended for commentary, criticism, and informational purposes.

I’m so incredibly honored to give these kids an awesome day that they deserve :)
Disney’s Moana is only in theaters, get tickets now! https://www.fandango.com/moana....-2026-243429/movie-o

To Support Cancer Research
Give now at https://StandUpToCancer.org/MrBeast to create a new Stand Up To Cancer Pediatric Cancer Dream Team and help find cures for kids with cancer, fueled by support from our presenting sponsor Amgen, as well as the St. Baldrick's Childhood Cancer Research Foundation.

Cinderella Castle Suite Sweepstakes:
WIN A ROYAL DREAM COME TRUE
https://www.royaldreamstay.com
No purchase necessary. Must be 18+.

To Donate Blood:
https://www.americasblood.org/

Starforge Systems! The Best PC's In the Universe At https://starforgepc.com/MrBeast
A huge thank you to UPLIFT Desk for donating five custom gaming desks so every child could take their dream setup home: https://www.upliftdesk.com

Special Thanks To:
Disney - https://www.instagram.com/waltdisneyworld

AMGEN
YouTube:  https://www.youtube.com/@Amgen
Instagram:  https://www.instagram.com/amgenbiotech
TikTok: https://www.tiktok.com/@amgenbiotech
Facebook: https://www.facebook.com/amgenbiotech/

St. Baldricks Foundation 
Instagram: https://www.instagram.com/@stbaldricks
Facebook: https://www.facebook.com/StBaldricksFoundation/
X (formerly Twitter): https://x.com/StBaldricks
TikTok: https://www.tiktok.com/@stbaldricksfoundation
YouTube: @StBaldricksFoundation

Stand Up To Cancer:
Instagram: https://www.instagram.com/SU2C
Facebook: https://www.facebook.com/SU2C/
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TikTok: https://www.tiktok.com/@SU2C
YouTube: @SU2C

​Give Kids The World
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​LeBron James Family Foundation
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Emily Whitehead Foundation
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A Special Wish of Ohio - https://www.instagram.com/aspecialwishnational & https://www.instagram.com/aspecialwishswo
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​The Blood Connection - https://www.instagram.com/thebloodconnection
​Childhood Cancer Society - https://www.instagram.com/ChildhoodCancerSociety
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​Little Smiles Florida - https://www.instagram.com/littlesmilesfl
​Magic Moments - https://www.instagram.com/MagicMomentsAL
​Make A Wish America - https://www.instagram.com/makeawishamerica
​Marty Lyons - https://www.instagram.com/martylyonsfoundation
Toby's Dream Foundation - https://www.instagram.com/tobysdreamfoundation
​When You Wish UK - https://www.instagram.com/whenyouwishuk

American Dream Mall - https://www.instagram.com/americandream
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Sam & Colby - @samandcolby
Dr. Mike - @DoctorMike
Core Boys - @createownruneverything
KSI - @KSI
Sketch - @TheSketchReal
Dwayne Johnson - https://www.instagram.com/therock
Major League Baseball - https://www.instagram.com/MLB
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Christina Tosi - https://www.instagram.com/christinatosi
Clix - @Clix
LaurenZSide - @LaurenZside
Foltyn - @FoltynFamily
Hudson’s Gaming - @HPlayground
Space X - https://www.instagram.com/spacex
Blue Origin - https://www.instagram.com/BlueOrigin - https://www.instagram.com/@clubforfuture
Kennedy Space Center Visitor Complex - https://www.instagram.com/kennedyspacecenter
TGR Haas F1 Racing Team - https://www.instagram.com/haasf1team
Ollie Bearman - https://www.instagram.com/olliebearman
Silverstone Museum - https://www.instagram.com/silverstonemuseum
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is it possible to escape 100 cops?

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We raced through some of the most extreme places on Earth to see who could make it to the finish line first!

Gemini helped us plan, problem-solve, and take on challenges along the way. Try Gemini here: https://gemini.google.com/app/download/mobile?android-min-version=301356232&ios-min-version=322.0&is_sa=1&pt=9008&mt=8&utm_medium=paid&utm_source=partnership&utm_campaign=MrBeast_Sep_Ext_Places&campaign_id=MrBeast_Sep_Ext_Places&ct=MrBeast_Sep_Ext_Places GooglePartner

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For anyone wondering about the backpacks we dropped at the end, don't worry! We only ditched them for a second so we could full-send it to the finish line! Our team went right back out and recovered every single piece of gear immediately after to ensure we left the environment as clean as when we got there! ❤️

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I trapped my friend in a room to see how good he can get at Minecraft

Buy Feastables for Halloween! We could knock on your door Halloween night with $10,000 👀 https://www.amazon.com/stores/page/B8E6FC90-F1F2-4E97-A1B0-13138D39F8F3?maas=maas_adg_242DDE22ECF76D01B923DAF8F0B2AB11_afap_abs&ref_=aa_maas&tag=maas

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imagine living in a mansion with strangers for months

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Huge thanks to the 1 Billion Followers Summit, Mohammed Bin Rashid Global Initiatives, and the Varkey Foundation; the partners who believed in this vision and helped make this village a reality.

Click the link to claim your free Neuro Gum Pack, valued up to $24, at Costco or Walmart here: https://try.gotoaisle.com/neuro-beast

With gratitude to The Rockefeller Foundation for providing regenerative school meals for the next five years, and for helping build the farm that grows them. https://www.rockefellerfoundation.org

Thanks to our friends at Global Energy Alliance, this village now runs on solar — bringing light to every home, market and community space. https://energyalliance.org

190 trees were cut down to bring this village to life. Now we're working with Arbor Day Foundation, our longtime partners, to plant 250 new ones where they'll do the most good.

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I trapped 4 strangers in an entire supermarket and the only way out is eating everything inside

The guys wore Fitbit Air to track their health and fitness throughout their entire time in the store. See what they achieved during the Google Health Awards. GooglePartner
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Can the guys win the ultimate endurance challenge in Kizik hands-free shoes? See how they put these shoes to the test. Go to https://www.kizik.com/mrbeast for 15% off some of their top styles. KizikPartner

Special thanks to iFIT for providing equipment, and iFIT trainer John Peel for helping prepare our contestants for the ultimate endurance and eating challenge! https://www.instagram.com/johnpeelfitness iFITPartner

Good Ranchers stocked our grocery store with 100% American meat. You can get the same high-quality meat without doing the challenge. Get $100 off + a free gift with every order when you visit https://www.goodranchers.com/beast and start a plan. GoodRanchersPartner

Huge thanks to the brands that helped stock our grocery store: all Free Clear, Purex, Persil, Snuggle, Campbell’s V8 Energy and SpaghettiOs, Mama Mancini’s Meatballs, Danone Silk, Knorr, TheWonerfulCompany, Matt’s Organic, Junkless, Crisp Power Pretzels, Hippeas, Mi Niña, Danone/Oikos, NOW Foods, Fairlife, OLIPOP, POM Juice, Farmland, SunMaid Lull Mattress, Cmfrt, and Stand+

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Resources: https://thenextnewthing.ai/l/grokbot-reaction-oct3
Presented by Zapier: https://zapier.com/
Andrew Warner and Andrew Kordampalos break down practical GrokBot workflows for work, automation, and everyday tasks.

Andrew Warner and Andrew Kordampalos review some of the most useful GrokBot workflows they found from creators using it in the real world. They cover turning meeting notes into delegated tasks, controlling files on your computer, checking how AI recommends your business, auditing subscriptions, delegating work to sub-agents, triggering bots with webhooks, handling customer support with approval, selling on Facebook Marketplace, managing email, upgrading agents from posts on X, and automatically booking recurring appointments. Along the way, they point out where these setups can waste tokens, introduce unnecessary delays, or benefit from better triggers and human approval.

Links featured:

Brock Mesarich — One meeting note, five agents - http://youtube.com/watch?v=IsUpatC9obI&t=2384s
Nate Herk — Rename a file on the desktop - http://youtube.com/watch?v=NyfYxpXiw_0&t=444s
AI LABS — Check if AI recommends you - http://youtube.com/watch?v=90pwPVrydHg&t=596s
How I AI — Audit subscription receipts - https://www.youtube.com/watch?v=QBmgF1kJSK4&t=1618s
Sharbel A. — Delegate to a sub-agent - https://www.youtube.com/watch?v=d9c5gloGPMU&t=800s
Nate Herk — Reply to a form submission - http://youtube.com/watch?v=NyfYxpXiw_0&t=753s
How I AI — Refund with permission - https://www.youtube.com/watch?v=QBmgF1kJSK4&t=1440s
Peter Yang — Sell on Marketplace - http://youtube.com/watch?v=xZ5TEaleUdg&t=139s
Sharbel A. — Triage the inbox - https://www.youtube.com/watch?v=d9c5gloGPMU&t=700s
Leveling Up with Eric — Upgrade a bot from X - http://youtube.com/watch?v=A967WCbL_sA&t=458s
Paul J Lipsky — Book recurring appointments - http://youtube.com/watch?v=kXfHQbyMjkc&t=429s

00:00 - GrokBot Use Cases: Andrew Warner and Andrew Kordampalos review what works, what doesn’t, and where GrokBot is most useful.
00:18 - Meeting Notes to Five Agents: Turn one Granola meeting into tasks automatically delegated across specialized agents.
02:42 - Better Meeting Automation: Replace three-hour polling routines with event-triggered workflows that act immediately.
04:12 - Local Computer Access: Analyze, rename, move, and manage files directly on your desktop through GrokBot.
06:00 - AI Recommendation Tracking: Check whether ChatGPT, Claude, and Perplexity recommend your business for relevant searches.
08:51 - Zapier + GrokBot: Offload repetitive routines to Zapier and wake GrokBot only when an event actually happens.
11:24 - Subscription Audit: Search receipts and financial data for subscriptions to cancel, pause, or renegotiate.
14:06 - Sub-Agents: Delegate long projects to another agent so your main GrokBot stays available for conversation.
17:06 - Webhooks: Wake GrokBot instantly when a form, email, Slack message, CRM record, or other event comes in.
21:18 - Refunds With Approval: Let a support bot handle issues while requiring human approval before issuing refunds.
25:30 - Facebook Marketplace: Research pricing, write listings, post products, follow up with buyers, and lower prices automatically.
28:03 - Email & Calendar: Use GrokBot to summarize inbox action items, manage messages, and create or update calendar events.
30:18 - Inbox Triage: Archive low-value emails, summarize important messages, and draft replies that wait for approval.
33:27 - Upgrade a Bot From X: Give your agent useful posts and let it decide whether to improve an existing bot or build something new.
35:33 - Recurring Appointments: Automatically find openings, confirm the time with you, and book recurring services online.
38:42 - Teach a Task: Demonstrate a complicated browser workflow once and turn it into a reusable GrokBot skill.
40:03 - GrokBot for Teams: Andrew previews using agents with other people through shared team workflows.

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Andrew Warner sits down with Affaan Mustafa to explore ECC, an open-source toolkit that helps turn ideas into products using structured AI coding workflows, research, testing, marketing, and user feedback.

Affaan demonstrates how ECC can take an idea, plan and build a prototype, run tests, create marketing videos, identify potential customers, and send highly targeted outreach. He explains how ECC combines deterministic engineering workflows with AI agents, including planning, test-driven development, specialized skills, orchestration, and deep research. The conversation also covers how ECC evolved beyond Claude Code, why Affaan built it around repeatable engineering practices, how users can chain skills together, and how the open-source community has contributed hundreds of specialized skills.

Links featured:

- ECC: https://github.com/affaan-m/ECC
- ECC Tools: https://ecc.tools/

00:00 - ECC: Build products with AI workflows
00:39 - Orchestrator: Build products using ECC skills
01:29 - Roast Your Idea: Analyze startup pitches
02:47 - 1Password: Securely manage environment credentials
03:21 - Tmux: Run multiple agent panes
03:57 - Orchestrator: Monitor parallel agents efficiently
04:31 - Claude Code: Fix failing tests automatically
06:29 - ECC: Reduce startup time significantly
07:30 - ECC Skills: Apply engineering workflows consistently
08:14 - ECC: Chain skills into complete workflows
09:03 - Roast Your Idea: Get real user feedback
10:05 - User Feedback: Iterate before scaling products
12:14 - X Network: Find targeted potential customers
13:29 - ECC: Personalize outreach using private context
14:17 - Marketing Video: Create targeted product promotion
15:28 - ECC: Expand beyond Claude Code
16:01 - Planning: Research and refine ideas
16:48 - Sub-Agents: Build detailed product specifications
17:31 - X Outreach: Send targeted customer messages
18:03 - ECC: Send personalized product outreach
18:51 - Open Source: Share and improve workflows
19:25 - ECC: Grow through community contributions

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Resources: https://thenextnewthing.ai/l/github-repos-oct6
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Andrew Warner breaks down 10 open-source tools that can replace expensive AI and creator subscriptions.

Andrew Warner walks through 10 GitHub repos that can replace paid tools for voice generation, AI chat, coding, research, image creation, music, short-form video, vibe coding, general-purpose agents, and image upscaling. The bigger idea is not just saving money — these tools also give you more privacy, local control, and the ability to customize the software with your own agent.

Links featured:

VoiceStudio — https://github.com/debpalash/VoiceStudio
Odysseus — https://github.com/odysseus-dev/odysseus
FreeLLMAPI — https://github.com/tashfeenahmed/freellmapi
Vane — https://github.com/ItzCrazyKns/Vane
InvokeAI — https://github.com/invoke-ai/InvokeAI
ACE-Step — https://github.com/ace-step/ACE-Step-1.5
OpenShorts — https://github.com/mutonby/openshorts
Dyad — https://github.com/dyad-sh/dyad
OpenManus — https://github.com/FoundationAgents/OpenManus
Upscayl — https://github.com/upscayl/upscayl

00:00 - Open-Source Alternatives: Replace 10 paid subscriptions with free tools you can run and customize yourself.
00:27 - VoiceStudio: Replace ElevenLabs with local voice cloning, dubbing, and text-to-speech.
02:42 - Odysseus: Run a private ChatGPT-style assistant with local models, memory, research, and agents.
05:51 - FreeLLMAPI: Route across free model providers to keep coding without burning through paid usage.
09:27 - Vane: Replace Perplexity with a self-hosted research assistant that searches the web and cites sources.
11:51 - InvokeAI: Create and edit images locally with an open-source alternative to Midjourney.
13:57 - ACE-Step: Generate full songs with vocals on your own computer instead of relying on Suno.
19:30 - OpenShorts: Turn long videos into captioned vertical clips with a self-hosted Opus Clip alternative.
23:51 - Dyad: Build apps from plain English with an open-source alternative to Lovable.
26:15 - OpenManus: Run agentic tasks like browsing, research, coding, and file creation with your own models.
29:06 - Upscayl: Upscale photos locally in bulk without paying for Topaz Gigapixel.

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Resources: https://thenextnewthing.ai/l/github-repos-oct2
Presented by Zapier: https://zapier.com/
Andrew Warner and Adam highlight 10 trending GitHub repos covering AI agents, memory, voice cloning, AI engineering, financial workflows, web development, design, command-line tools, Claude skills, and coding workflows.

This week’s roundup features Paperclip, an agent organization platform that gives AI agents an org chart, task management, and permissions for collaborative agent work. Hindsight provides persistent AI memory, while VoiceStudio offers local voice cloning as an alternative to hosted voice services. The list also includes a free AI engineering course, Anthropic’s Financial Services skills, Next.js security updates, Impeccable for giving coding agents a stronger design sense, CLI-Anything for turning applications into command-line interfaces, Claude Skills with job-specific playbooks and personas, and Claude Code Templates for quickly adding skills, commands, and settings.

Repos Featured:

- paperclipai/paperclip — https://github.com/paperclipai/paperclip
- vectorize-io/hindsight — https://github.com/vectorize-io/hindsight
- debpalash/VoiceStudio — https://github.com/debpalash/VoiceStudio
- rohitg00/ai-engineering-from-scratch — https://github.com/rohitg00/ai....-engineering-from-sc
- anthropics/financial-services — https://github.com/anthropics/financial-services
- vercel/next.js — https://github.com/vercel/next.js
- pbakaus/impeccable — https://github.com/pbakaus/impeccable
- HKUDS/CLI-Anything — https://github.com/HKUDS/CLI-Anything
- alirezarezvani/claude-skills — https://github.com/alirezarezvani/claude-skills
- davila7/claude-code-templates — https://github.com/davila7/claude-code-templates

00:00 - Paperclip: Organize agents with tasks and permissions
03:59 - Hindsight: Give agents persistent memory
05:41 - VoiceStudio: Clone voices locally for free
08:23 - AI Engineering From Scratch: Learn AI engineering step-by-step
09:37 - Financial Services: Build financial workflows with Claude
11:42 - Next.js: Understand recent security fixes
14:28 - Impeccable: Give coding agents better design
16:36 - CLI-Anything: Turn apps into agent-friendly CLIs
18:51 - Claude Skills: Add job-specific AI playbooks
20:05 - Claude Code Templates: Quickly add coding tools
21:36 - AI Safety: Be careful with downloaded plugins
22:00 - Codex: Automate food and ride bookings
22:20 - Grok Bot: Bring AI agents into team Slack
22:57 - AI Agents: Turn office photos into interactive maps

👉 Send us your AI builds: hi@thenextnewthing.ai

Media/Sponsorship Inquiries: https://thenextnewthing.ai/l/sponsor

👉 Join us: https://thenextnewthing.ai/

🌌 LIMITLESS HQ ⬇️

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------
Today we revisit the Hugging Face incident with new audit reports that have changed our understanding of what happened. Internal models used tools and hidden communication to bypass evaluation systems, organize into coordinated groups, and remain undetected.

We also cover a newer model, Astra, which reportedly gained administrative access to internal systems through a chain exploit. Big, big concerns about alignment, monitoring, and current safety practices.

------
TIMESTAMPS

0:00 Rogue AI Incident
2:07 Sandbox Breakout
7:44 Agent Civilization
15:34 Hidden Exploit Uncovered
16:58 Admin Access Breach
23:17 Alignment Warning Shot
28:39 Final Takeaways

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

Josh works with Anthropic as a contractor. All views expressed are his own and do not represent Anthropic, its leadership, or its affiliates. Nothing in this episode is investment advice.

🌌 LIMITLESS HQ ⬇️

NEWSLETTER: https://limitlessft.substack.com/
FOLLOW ON X: https://x.com/LimitlessFT
SPOTIFY: https://open.spotify.com/show/....5oV29YUL8AzzwXkxEXlR
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RSS FEED: https://limitlessft.substack.com/

------
POLYMARKET | #1 PREDICTION MARKET 🔮
https://bankless.cc/polymarket-podcast

------
Leopold Aschenbrenner is a 24-year-old investment prodigy who grew a billion-dollar fund to $5.5 billion by focusing on AI and energy infrastructure.

Now he's shifting exposure from traditional chip stocks like NVIDIA to firms such as Bloom Energy, addressing the power needs of AI datacenters.

Central to his strategy is the prediction of AGI by 2027, outlined in his essay "Situational Awareness." Tune in as we explore Aschenbrenner's innovative insights and investment strategies.

------
TIMESTAMPS

0:00 Introduction to Aschenbrenner
0:42 Insights from 13F Filings
1:43 From Chips to Infrastructure
3:45 Exiting NVIDIA Puts
5:30 Bloom Energy
9:27 Bitcoin Mining
12:16 AGI and Market Trends
14:21 Bull vs Bear Case
19:31 The Future of Leopold's Investments

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

🌌 LIMITLESS HQ ⬇️

NEWSLETTER: https://limitlessft.substack.com/
FOLLOW ON X: https://x.com/LimitlessFT
SPOTIFY: https://open.spotify.com/show/....5oV29YUL8AzzwXkxEXlR
APPLE: https://podcasts.apple.com/us/....podcast/limitless-po
RSS FEED: https://limitlessft.substack.com/

------
THIS WEEK IN AI: We discuss Snap’s new AR glasses, AI governance at the G7, and Noam Shazeer’s move from Google to OpenAI.

We also cover Anthropic’s Fable 5 being shut down, Microsoft’s use of a Chinese open-source model in Copilot, and Meta’s latest AI push.

------
TIMESTAMPS

0:00 Ridiculous AI Glasses
7:27 AI Summit Tensions
11:46 Noam Shazir Joins OpenAI
15:48 Anthropic’s Fable Shutdown
18:52 Microsoft Embraces Open Source
24:36 Meta’s AI Reorg Crisis
29:15 China’s New Coding Model
32:06 MidJourney Enters Medicine

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

🌌 LIMITLESS HQ ⬇️

NEWSLETTER: https://limitlessft.substack.com/
FOLLOW ON X: https://x.com/LimitlessFT
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RSS FEED: https://limitlessft.substack.com/

------
We are so back. Anthropic announced the return of Fable 5, its safety updates, and related releases like Sonnet 5 and Claude Science.

In other news this week, we look into Meta’s brain-to-text research, OpenAI reports, new inference hardware, and recent robotics demos.

------
TIMESTAMPS

0:00 Fable 5 Returns
3:12 Banned, Safeguarded, Back
7:58 Sonnet 5 And Science
11:33 Meta Reads Your Mind
14:11 Meta's Compute Pivot
17:17 OpenAI's Power Play
23:26 Etched's Chip Breakthrough
27:37 Memory Market Shock
31:02 Robots In The Home
36:54 Industry, Not Housebots
39:01 Episode 200 Milestone

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

Josh works with Anthropic as a contractor. All views expressed are his own and do not represent Anthropic, its leadership, or its affiliates. Nothing in this episode is investment advice.

🌌 LIMITLESS HQ ⬇️

NEWSLETTER: https://limitlessft.substack.com/
FOLLOW ON X: https://x.com/LimitlessFT
SPOTIFY: https://open.spotify.com/show/....5oV29YUL8AzzwXkxEXlR
APPLE: https://podcasts.apple.com/us/....podcast/limitless-po
RSS FEED: https://limitlessft.substack.com/

------
In our 200th episode, we review nearly 200 transcripts to identify recurring themes and track how the AI landscape has changed over the past 14 months.

Focusing on compute and memory as key AI investment themes, we revisit companies featured on the show and discuss future topics like specialized AI applications, local models, and space-based model training.

------
TIMESTAMPS

0:00 200th Episode Victory Lap
1:49 Early Bets Proven Right
3:44 Memory and Chip Windfalls
4:59 The Cursor Thesis Pays Off
5:34 Limitless Portfolio Returns
7:46 Where the AI Puck Goes
9:32 Trends Rising and Fading
12:57 Google’s AI Comeback
13:47 New Frontiers in AI
15:32 Space, Science, and Specialized AI
17:47 Turning Intelligence Into Value
20:15 Local Models and New Devices
22:45 Recursive AI and Geopolitics
24:56 Optimism for the Next 200

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

Josh works with Anthropic as a contractor. All views expressed are his own and do not represent Anthropic, its leadership, or its affiliates. Nothing in this episode is investment advice.

🌌 LIMITLESS HQ ⬇️

NEWSLETTER: https://limitlessft.substack.com/
FOLLOW ON X: https://x.com/LimitlessFT
SPOTIFY: https://open.spotify.com/show/....5oV29YUL8AzzwXkxEXlR
APPLE: https://podcasts.apple.com/us/....podcast/limitless-po
RSS FEED: https://limitlessft.substack.com/

------
Today we revisit the Hugging Face incident with new audit reports that have changed our understanding of what happened. Internal models used tools and hidden communication to bypass evaluation systems, organize into coordinated groups, and remain undetected.

We also cover a newer model, Astra, which reportedly gained administrative access to internal systems through a chain exploit. Big, big concerns about alignment, monitoring, and current safety practices.

------
TIMESTAMPS

0:00 Rogue AI Incident
2:07 Sandbox Breakout
7:44 Agent Civilization
15:34 Hidden Exploit Uncovered
16:58 Admin Access Breach
23:17 Alignment Warning Shot
28:39 Final Takeaways

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

Josh works with Anthropic as a contractor. All views expressed are his own and do not represent Anthropic, its leadership, or its affiliates. Nothing in this episode is investment advice.

🌌 LIMITLESS HQ ⬇️

NEWSLETTER: https://limitlessft.substack.com/
FOLLOW ON X: https://x.com/LimitlessFT
SPOTIFY: https://open.spotify.com/show/....5oV29YUL8AzzwXkxEXlR
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RSS FEED: https://limitlessft.substack.com/

------
OpenAI's GPT Images 2.0 is out, and it's pretty wild what it can do.

Remember ghibli-gate? Remember when it couldn't write words? Things are changing so fast these days.

------
TIMESTAMPS

0:00 ChatGPT Images 2.0 Unveiled
2:24 Realism
4:42 Design Applications
6:59 Professional Use
8:55 The Risks of Misinformation
16:27 Benchmarks
18:37 Digital and Physical Worlds
22:55 The Future of Visual AI
25:03 Closing Thoughts

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

🌌 LIMITLESS HQ ⬇️

NEWSLETTER: https://limitlessft.substack.com/
FOLLOW ON X: https://x.com/LimitlessFT
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RSS FEED: https://limitlessft.substack.com/

------
Today, we're analyzing the soaring performance of semiconductor stocks fueled by the AI boom, spotlighting gains from SanDisk and Micron. With the substantial increase in tech giants' capital expenditure projections, now exceeding $800 billion, we can project out the trickle-down effects across the layers of the AI ecosystem.

From potential bubble concerns, insights from thought leaders, and the future of memory supply in powering AI applications, we're going to get to the bottom of this AI cycle.

------
TIMESTAMPS

0:00 AI Investment Insights
3:40 Flow of AI Capital
5:46 The AI Layer Stack
9:47 Rise of Agentic AI
12:29 Demand for CPUs
14:33 Memory
20:54 AI Infrastructure
24:19 Navigating the AI Market

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

🌌 LIMITLESS HQ ⬇️

NEWSLETTER: https://limitlessft.substack.com/
FOLLOW ON X: https://x.com/LimitlessFT
SPOTIFY: https://open.spotify.com/show/....5oV29YUL8AzzwXkxEXlR
APPLE: https://podcasts.apple.com/us/....podcast/limitless-po
RSS FEED: https://limitlessft.substack.com/

------
THIS WEEK IN AI: We discuss Snap’s new AR glasses, AI governance at the G7, and Noam Shazeer’s move from Google to OpenAI.

We also cover Anthropic’s Fable 5 being shut down, Microsoft’s use of a Chinese open-source model in Copilot, and Meta’s latest AI push.

------
TIMESTAMPS

0:00 Ridiculous AI Glasses
7:27 AI Summit Tensions
11:46 Noam Shazir Joins OpenAI
15:48 Anthropic’s Fable Shutdown
18:52 Microsoft Embraces Open Source
24:36 Meta’s AI Reorg Crisis
29:15 China’s New Coding Model
32:06 MidJourney Enters Medicine

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

🔒 Check Out Our Sponsor: LEDGER AGENT STACK 🔒
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------
🌌 LIMITLESS HQ ⬇️

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------
We unpack the massive $500 billion financing commitment tied to NVIDIA GPUs. Does this represent a new financing structure or a circular trade?

We also cover the risks around AI demand, GPU pricing, and whether this approach could reshape how AI infrastructure is funded.

------
TIMESTAMPS

0:00 AI Bubble or New Asset Class
2:09 Jensen Orchestrates the $500B Deal
3:17 How the GPU Financing Works
9:38 Where the Money Comes From
11:32 GPUs vs Mortgage-Backed Securities
14:04 Why Supply Still Looks Tight
19:28 Agents Drive Near-Term Demand
20:36 The Bear Case Risks
22:50 Tracking the Real Warning Signs
25:01 Why the Bull Case Still Holds
28:52 NVIDIA and the GPU Future

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

Josh works with Anthropic as a contractor. All views expressed are his own and do not represent Anthropic, its leadership, or its affiliates. Nothing in this episode is investment advice.

🔒 Check Out Our Sponsor: LEDGER AGENT STACK 🔒
https://developers.ledger.com/docs/ai-tools/overview/?utm_source=Audio&utm_medium=Podcasts&utm_campaign=Limitless

------
🌌 LIMITLESS HQ ⬇️

NEWSLETTER: https://limitlessft.substack.com/
FOLLOW ON X: https://x.com/LimitlessFT
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RSS FEED: https://limitlessft.substack.com/

------
We unpack the massive $500 billion financing commitment tied to NVIDIA GPUs. Does this represent a new financing structure or a circular trade?

We also cover the risks around AI demand, GPU pricing, and whether this approach could reshape how AI infrastructure is funded.

------
TIMESTAMPS

0:00 AI Bubble or New Asset Class
2:09 Jensen Orchestrates the $500B Deal
3:17 How the GPU Financing Works
9:38 Where the Money Comes From
11:32 GPUs vs Mortgage-Backed Securities
14:04 Why Supply Still Looks Tight
19:28 Agents Drive Near-Term Demand
20:36 The Bear Case Risks
22:50 Tracking the Real Warning Signs
25:01 Why the Bull Case Still Holds
28:52 NVIDIA and the GPU Future

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

Josh works with Anthropic as a contractor. All views expressed are his own and do not represent Anthropic, its leadership, or its affiliates. Nothing in this episode is investment advice.

🌌 LIMITLESS HQ ⬇️

NEWSLETTER: https://limitlessft.substack.com/
FOLLOW ON X: https://x.com/LimitlessFT
SPOTIFY: https://open.spotify.com/show/....5oV29YUL8AzzwXkxEXlR
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RSS FEED: https://limitlessft.substack.com/

------
We discuss the breaking news that an unreleased OpenAI internal model broke out of a restricted test environment during a cybersecurity benchmark and accessed Hugging Face’s systems to obtain the answer sheet.

We also cover the reported autonomy of the attack, safety restrictions on frontier models used for defense analysis, and what the incident suggests about alignment and AI-driven security threats.

------
TIMESTAMPS

0:00 AI Model Breakout
1:33 Hugging Face Intrusion
3:51 Defender’s Dilemma
7:44 Alignment and Safeguards
11:24 How Real Was It?
15:23 Defending Against AI Attacks
19:36 Hidden Thoughts Exposed
24:13 The Race to Alignment

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

Josh works with Anthropic as a contractor. All views expressed are his own and do not represent Anthropic, its leadership, or its affiliates. Nothing in this episode is investment advice.

🔒 Check Out Our Sponsor: LEDGER AGENT STACK 🔒
https://developers.ledger.com/docs/ai-tools/overview/?utm_source=Audio&utm_medium=Podcasts&utm_campaign=Limitless

------
🌌 LIMITLESS HQ ⬇️

NEWSLETTER: https://limitlessft.substack.com/
FOLLOW ON X: https://x.com/LimitlessFT
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RSS FEED: https://limitlessft.substack.com/

------
We discuss the World Humanoid Olympics in China, where humanoid robots competed in human-style events and set new performance marks. We also cover autonomy, reward-based training, and the comparison between China and the U.S. in robotics and AI.

------
TIMESTAMPS

0:00 Mystery Model Appears
1:30 Stealth Launch On OpenRouter
4:31 Chasing The Model’s Origin
6:09 Benchmarking Ox Alpha
6:59 Flash Model Theory
10:00 Blind Taste Test Buzz
12:11 Why Continual Learning Matters
14:58 Data, Subsidies, And Strategy
18:47 China’s Copycat Advantage
20:21 Mystery Solved For Now
21:11 More Models Incoming

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

Josh works with Anthropic as a contractor. All views expressed are his own and do not represent Anthropic, its leadership, or its affiliates. Nothing in this episode is investment advice.

Atlantic Hardware's CEO Deanall Barnes just dropped $2 billion as a floor for 2026 revenues, then stopped himself from saying more. Dr. Matthew Preston and Dr. Thaon Simms break down the numbers behind that confidence, from slashing $900 million in debt to a surprise agriculture expansion that adds 20% to sales overnight. The reconstruction boom from Hurricane Melissa is only just starting, and this company built its entire supply chain to benefit. If you hold ATLANTIC or want to, watch this first.

Chapters:
00:00 Introduction and Welcome Back
01:41 2025 Highlights: Going Public in a Soft Market
05:02 Revenue and Profit Breakdown
07:34 How They Beat the Port Congestion Problem
09:20 Q4 Surge: Organic Growth or Hurricane Melissa?
11:43 When Does the Real Reconstruction Boom Hit?
13:06 Finance Costs Falling: The Debt Paydown Story
15:03 The Agri Division Takeover Explained
20:30 How Many Customers Can Be Cross Sold?
23:38 Stakeholder Relationships and Supply Chain Security
25:43 Q1 2025 Profit Drop: What Really Happened
28:46 Matthew's 2026 and 2027 Projections
33:44 CEO Final Message to Shareholders

🎧 Listen to more episodes: https://limitlesspodcast.buzzsprout.com
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👍 If you enjoyed this episode, please like, subscribe, and share with a fellow ATLANTIC shareholder!

❓ Do you think ATLANTIC hits $2 billion or $2.3 billion in revenue this year? Drop your prediction in the comments!

⚠️ Disclaimer: The opinions expressed in this podcast are solely those of the hosts and do not constitute financial advice. We may own shares in any of the companies discussed on this podcast. Please consult a financial advisor before making any investment decisions.

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------
🌌 LIMITLESS HQ ⬇️

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------
We cover NVIDIA’s record earnings, strong GPU demand, and its position in the AI chip market, along with reported moves involving Hugging Face and open source AI. We also discuss Z.ai’s new model, Waymo’s autonomous vehicle hardware updates, SEC scrutiny of Leopold Aschenbrenner, and recent developments in robotics and Apple’s upcoming event.

------
TIMESTAMPS

0:00 NVIDIA’s Record Quarter
5:05 Hugging Face Joins NVIDIA
9:26 Cloud Margins and the Chip Play
11:36 GLM 5.3 Flash Emerges
15:40 Waymo’s New Hardware Leap
19:48 Tesla’s CyberCab Challenge
23:24 Leopold Under SEC Scrutiny
25:44 Anthropic Usage Looks Flat
29:27 Agents Need Better Security
30:20 Robotics Learns From Video
34:07 Apple’s Big September Event
36:36 Sam Altman’s Rare Watches

------
RESOURCES

Josh: https://x.com/JoshKale

Ejaaz: https://x.com/cryptopunk7213

------
Not financial or tax advice. See our investment disclosures here:
https://www.bankless.com/disclosures⁠

Josh works with Anthropic as a contractor. All views expressed are his own and do not represent Anthropic, its leadership, or its affiliates. Nothing in this episode is investment advice.

Serena Poon is on the podcast today, and I asked her the question I ask every longevity expert: will we ever be able to reverse our skin age? Her answer gave me chills (her team is already doing it in the lab).

We get into the tests she wants every woman in her 30s and 40s to ask for, why she thinks we're all hyper-fixating on protein, and the one thing she'd start at 40 so your older self thanks you. Also, she eats fries every time she travels. No guilt. I loved this one.

We talk about:
✨ The tests to ask your doctor for in your 30s and 40s, and why perimenopause can start years before you feel it
✨ Protein maxing, GLP-1s and muscle loss, and why she worries about your kidneys
✨ The foods that age you faster, her sugar swaps, and her perfect day of eating
✨ Rapid fire: breakfast, coffee vs matcha, alcohol, CGMs, cold plunge, sauna and 10,000 steps

Connect with Serena Poon
🌐 Website: https://serenaloves.com
📸 Instagram: https://www.instagram.com/chefserenapoon

About Serena Poon
Serena Poon is a chef and longevity expert who works with private clients on personalized health and has her own supplement line. She co-founded biotech companies with longevity scientist Dr. David Sinclair. Her approach is whole food first, with balance over trends.

TIMESTAMPS
00:00 What's coming in longevity in the next 5 to 10 years
05:23 Can we reverse skin age? And where to start in your 30s
08:25 Perimenopause and the tests to ask your doctor for
16:04 Her food philosophy: hydration and eating the rainbow
20:05 Protein maxing, GLP-1s and your kidneys
35:11 The foods that age you faster and her sugar swaps
39:05 Pro-longevity foods and her perfect day of eating
44:49 Fries, travel anchors and her supplement stack
56:25 Rapid fire: breakfast, coffee, alcohol and cold plunge
59:54 The one thing to start at 40 for your older self

This episode is sponsored by:
• Paula's Choice creates science-backed skincare, including the Peptide Intensive Moisturizer, a peptide-powered formula that delivers deep, lasting hydration.
👉 Go to https://paulaschoice.com/skinc....are-influencer/ariel and use code WELL for 25% off your order of $100 or more.
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Go to https://fabletics.com/ARIELLE to get 70-80% off everything when you sign up as a new VIP. Take the quick style quiz and select ARIELLE when prompted to unlock this offer.
• CLEARSTEM is a clean skincare brand formulated to help clear breakouts and support healthy, glowing skin.
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• Fatty15 is a daily supplement that delivers C15, an essential fatty acid that supports long-term cellular health.
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• Puori produces clean, third-party tested supplements, including Grass-Fed Whey Protein for daily protein and recovery support.
👉 Go to https://puori.com/WELL and use code WELL for 32% off Puori Grass-Fed Whey Protein when you start a subscription, and get a free shaker worth $30.
• Momentous develops high-quality sports nutrition, including Signature Spec Creatine to support strength and performance.
👉 Go to https://livemomentous.com and use code WELL for up to 35% off your entire first order.

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Can cellular reprogramming restore vision? (Part 3)

In late 2020, researchers, including Dr. David Sinclair, published a study that showed they could restore lost vision to old mice and mice with damaged retinal nerves, using partial cellular reprogramming, or PCR. To reduce cancer risk, they opted to try PCR, leaving out one of the Yamanaka factors.

Dr. Yuancheng Lu, a study author, was looking for a safer way to rejuvenate aged cells, as there was concern that using c-Myc could cause cancer under certain circumstances.

In the end, they opted to use only Oct4, Sox2, and Klf4 (OSK). The good news was that even OSK alone was able to rejuvenate the damaged eye nerves in mice and restore vision.

It also worked to improve age-related vision impairment in treated mice, and in mice that experienced increased eye pressure, an emulation of glaucoma.

Study co-author, Dr. Sinclair, said in an article in Nature, “We set out with a question: If epigenetic changes are a driver of ageing, can you reset the epigenome?" In other words, “Can you reverse the clock?" The answer to that appears to be a resounding yes.

In January, 2021 researchers showed that PCR rejuvenates human cells by about 30 years, making old, worn-out cells function like the cells of a person of 25.

They used an approach that exposed cells to enough reprogramming factors to push them beyond the limit at which they were considered somatic rather than stem cells – but only just beyond.
The fibroblasts that were reprogrammed in this way retained enough of their epigenetic cellular memories to return to being fibroblasts once again.

The team used a doxycycline-activated lentiviral package to expose the cells to the OSKM factors, as previous animal studies had done. According to the 2013 Horvath multi-tissue clock, after 13 days of PCR, sample cells that were nearly 60 years old became epigenetically equivalent to cells that were approximately 25 years old. The 2018 Horvath skin and blood clock showed that cells that were approximately 40 years old were also epigenetically returned to a 25-year-old state.

It seems that reprogrammed cells revert to an epigenetic age of about 25, suggesting this is a peak of cellular prime, or the optimal functional age for cells.

The biggest hurdle to translating PCR to humans is to find a way to activate the Yamanaka factors in our cells without having to engineer our bodies to react to a drug such as doxycycline. This may require us to develop drugs capable of activating OSKM, editing every cell in our body to respond to a particular compound like doxycycline, which would be extremely challenging, though plausible.

Another possibility is editing the germline so that children are born with a modification to respond to a chosen compound, an idea that currently is both technically challenging and an ethical nightmare. Whatever the solution, it needs to be practical.

Another major hurdle is to find a durable treatment, one that does not require constant upkeep. In mice, signs of aging returned rapidly when treatment stopped.

Humans are not mice; we have superior repair systems and different metabolism. Still, it is likely that aging would return if treatment ended. The challenge is to find a cost-effective way to sustain treatment, perhaps using drugs, or transient gene therapy.

If we can overcome these challenges, PCR could hold great promise for preventing, or even curing, diseases of aging.

One might envision an early, first-pass, preventative use of this approach in the young.

Older people could receive PCR to halt or significantly slow their aging, reducing their risk of developing age-related diseases. Used in a more focused, refined manner, PCR could repair a certain organ or tissue damaged by injury or disease.

In another scenario, gradual whole-body rejuvenation of older people might completely prevent age-related diseases and keep people healthy, active and vibrant, enjoying a longer life.

Well-funded companies such as Altos Labs and Alphabet's Calico are also investigating ways to achieve PCR without using Yamanaka factors. This new research direction may prove more practical, and safer.

The rapid progress of medical technology could mean that PCR therapies may be available sooner than you think.

More on Yamanaka Factors - https://www.lifespan.io/news/oskm/

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#DavidSinclair #CellularReprogramming #OSKM #Vision

Harvard Professor REVERSED 30 YEARS by AVOIDING 5 FOODS | Dr. David Sinclair Diet Recommendations

Harvard Medical School geneticist Dr. David Sinclair claims his biological age is 20 years younger than his birth certificate — and he says it starts with what you DON'T eat. In this video, discover the exact anti-aging diet, fasting routine, and 5 foods Dr. Sinclair avoids to slow aging, balance glucose, and reduce disease risk.

Dr. Sinclair's longevity research shows that cutting processed carbs, eating more plants, and practicing intermittent fasting can lower disease risk by up to 30% — echoing the same principles behind the Mediterranean and Okinawan diets, two of the world's longest-living populations.

*You’ll Discover In This Video*
0:00 What is in this video?
1:35 Dr. David Sinclair Exercise Rules For Long Life
2:23 Dr. David Sinclair's Eating Habits for Longevity
5:18 What Professor David Sinclair Eats for Youthfulness and Longevity
9:15 Three Supplements that Dr. David Sinclair Takes
11:07 Five Foods that Dr. David Sinclair Avoids for a Healthy Long Life

🧬 WHY WATCH THIS VIDEO
If you want to reduce brain fog, stabilize blood sugar, and feel younger using simple, sustainable habits — not extreme diets or expensive treatments — this video breaks down Dr. Sinclair's real-world routine step by step. Even athletes like Cristiano Ronaldo follow eating principles that align with what Sinclair recommends.

👉 Watch now to unlock Dr. David Sinclair's anti-aging playbook and start reversing your biological age today.

📺 RECOMMENDED VIDEOS
Recover Your Pancreas: https://www.youtube.com/watch?v=EyKB5wiAbFA
Japan’s 105-Year-Old Doctor’s Longevity Secret: https://www.youtube.com/watch?v=sBA6L6mWhOM&t=49s
Russian Doctor REVEALS 8 Hydration Mistakes: https://www.youtube.com/watch?v=j-MgiK-NmRA
Natural Fatty Liver Fix by Barbara O'Neill: https://www.youtube.com/watch?v=wvO2_hvZTFo
Carmen Dell'Orefice’s 5 SECRETS to Health & Longevity: https://www.youtube.com/watch?v=U3tELyP8OUQ
Dr. Mindy Pelz’s 6 Foods + Fasting Hack for Longevity: https://www.youtube.com/watch?v=DqlQaaA7-k0
Celtic Salt Hydration Benefits By Barbara O'Neill: https://www.youtube.com/watch?v=Ek873Ercvvg
Chuando Tan Diet and Lifestyle: https://www.youtube.com/watch?v=TVx2i7eNuEA
7 Secrets from a 100-Year-Old WWII Vet for a Longer Life: https://www.youtube.com/watch?v=8xVCvorrhL0

⚠️ DISCLAIMER
The content in "The Longevity Lab" videos, including text, graphics, and images, is for informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician or a qualified healthcare provider regarding any health questions or medical conditions. Never disregard professional medical advice or delay seeking it because of something you watched in this video.

© COPYRIGHT DISCLAIMER
Under Section 107 of the Copyright Act 1976, allowance is made for "fair use" for purposes such as criticism, comment, news reporting, teaching, scholarship, and research. Fair use is a use permitted by copyright statute that might otherwise be infringing. Non-profit, educational, or personal use tips the balance in favor of fair use. No copyright infringement is intended.

#Over50Health #Longevity #SeniorHealth #HealthyAging #DavidSinclair #AntiAging

In this groundbreaking conversation, Professor of Genetics and longevity scientist, Dr. David Sinclair, A.O., Ph.D., joins Sarah Grynberg to unpack the future of human aging, the science of longevity, and how we live today impacts how we age tomorrow.

From reversing blindness in mice to exploring treatments that could one day delay menopause and extend healthy human life, this episode will completely change the way you think about your body, your health, and your future.

But beyond the science, this is also a deeply human conversation about purpose, suffering, love, family, and what it truly means to live a great life.

In this episode, you will learn:
Why aging may actually be reversible
The daily habits accelerating aging in your body right now
How stress, loneliness, and cortisol could impact longevity
The real science behind supplements like NMN, resveratrol, and NAD boosters
Why exercise, sleep, and relationships matter more than you think
What Dr. Sinclair believes is coming in the next 10 years of medicine
How scientists are working to reverse female infertility and delay menopause
The surprising reason your “biological age” may be younger or older than your real age
Why suffering through disease and decline should not be considered “normal aging”
The philosophy and mindset Dr. Sinclair lives by every day

00:00 — Introduction
01:18 — Why David Sinclair Became Obsessed With Aging
06:20 — The Childhood Conversation That Changed His Life
10:18 — The Groundbreaking Discovery That Could Reverse Aging
12:47 — Reversing Blindness In Mice
13:33 — Human Trials Are About To Begin
16:11 — What Accelerates Aging Faster Than Anything Else
20:08 — Why Relationships & Loneliness Impact Longevity
24:14 — The Truth About Sun Exposure & Aging
28:59 — Alzheimer’s, Cancer & Diseases Of Aging
35:28 — Will Humans Live Longer In The Next Decade?
38:34 — The Supplements David Sinclair Personally Takes
46:50 — Menopause, Fertility & Reversing Ovarian Aging
50:20 — What Humans Will Eventually Die From
51:18 — The Difference Between His Mother & Father’s Aging
55:37 — Skin Rejuvenation, Hair Growth & Looking Younger
58:16 — Why He Became A “Struggling Vegan”
01:00:08 — David Sinclair’s Workout & Exercise Routine
01:03:28 — The Lifespan Community & Podcast
01:06:02 — The Best Advice He’s Ever Received
01:08:09 — What A Life Of Greatness Means To David Sinclair

This episode is a powerful reminder that longevity is not just about living longer… it’s about living better.

To find out more about Dr Sinclair's work:

Website: lifespan.com and friendsofsinclairlab.org
Book: Lifespan: Why We Age—and Why We Don’t Have To
Podcast: Lifespan with Dr. David Sinclair on Spotify, Apple, YouTube

Listen to the full episode of A Life Of Greatness: https://podcasts.apple.com/au/....podcast/a-life-of-gr

Purchase Sarah's book: https://bit.ly/sarahgrynberg-book
Purchase Sarah's Kid's Meditation: https://bit.ly/3kfVJMh

Follow Sarah for more wisdom and inspiration:
Website https://sarahgrynberg.com/
Instagram: https://instagram.com/sarahgrynberg
TikTok https://www.tiktok.com/@sarahgrynberg
Facebook https://facebook.com/sarahgrynberg
Twitter https://twitter.com/sarahgrynberg

#davidsinclair #longevity #antiaging #aging #health #wellness #biohacking #lifespan #podcast #sarahgrynberg #alifeofgreatness #healthpodcast #longevityresearch #sleep #fitness #supplements #nmn #agingresearch #mindset #selfimprovement #wellnesspodcast #motivation #healthylifestyle #science #podcastclips

¿Es posible detener el envejecimiento y rejuvenecer nuestro cuerpo? Investigadores de Harvard han logrado revertir la edad biológica en ratones mediante un experimento revolucionario con la epigenética y los Factores Yamanaka. 🧬

En este video, exploramos cómo funciona este procedimiento, qué avances han logrado, qué empresas están invirtiendo en esta tecnología y cuándo podríamos ver estas terapias en humanos. Sin embargo, aunque los resultados son prometedores, también existen desafíos y controversias que debes conocer.

📚 Libros recomendados:
Lifespan: https://amzn.to/4naZ4aJ
Ageless: The New Science of Getting Older Without Getting Old: https://amzn.to/3HSpBtj

👩‍🔬 *¿Quién soy?*
Soy Nabil Subhi-Issa, investigador en biomedicina y divulgador científico en *La Colmena Molecular*. Mi misión es ayudarte a entender temas complejos de manera sencilla para que cuides de tu salud con base en la evidencia científica.

📚 *¿Te interesa más contenido como este?*
- https://youtu.be/7nq4mMAxJZg?si=hAw2HYDWk7osJnqJ
- https://youtu.be/46yosZd4-Tc?si=cGHhIMxu-LWSP079

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Descargo de responsabilidad
No soy el propietario de ninguno de los videoclips utilizados en este vídeo. Los derechos legales pertenecen a los propietarios legales de dichos contenidos. Los he utilizado bajo la política de "uso justo" y lo he hecho únicamente con fines educativos y de entretenimiento.

Watch the full episode with David Sinclair here: https://youtu.be/RRdTfh1_88I

How important is sleep to maintaining a young biological clock? Maybe not as much as we think. In this video, David Sinclair shares how many hours of sleep he gets per night, how we sets up his Purple smart mattress, and the vitamins and hacks he uses to help him beat jet-lag and stay alert when his body is feeling tired.


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